1887

Abstract

separated from armadillo tissues stored at -80 C is similar to that from human sources in its ability to take up H-labelled 3,4-dihydroxyphenylalanine (DOPA). Several inhibitors were studied which showed complete or partial inhibition of [H]DOPA uptake. These findings suggest that isolated from frozen tissue possesses an active uptake system for [H]DOPA.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-127-2-385
1981-12-01
2024-04-19
Loading full text...

Full text loading...

References

  1. Ambrose E.J., Antia N.H., Khanolkar S.R. 1974; Uptake of radioactive DOPA by M. leprae. Nature, London 249:854–855
    [Google Scholar]
  2. Ambrose E.J., Khanolkar S.R., Chulawalla R.G. 1978; A rapid test for bacillary resistance to dapsone. Leprosy in India 50:131–143
    [Google Scholar]
  3. Harris E.B., Prabhakaran K. 1975; Uptake of radioactive DOPA by Mycobacterium leprae. Microbios 12:119–124
    [Google Scholar]
  4. Hart P., D’Arcy, Rees R. J. W. 1960; Effect of macrocyclon in acute and chronic pulmonary tuberculosis infection in mice as shown by viable and total bacterial counts. British Journal of Experimental Pathology 41:414–421
    [Google Scholar]
  5. Khanolkar S.R. 1976 Metabolic studies on Mycobacterium leprae in vitro using radioisotopes. Ph.D. thesis: University of Bombay, India;
    [Google Scholar]
  6. Khanolkar S.R., Antia N.H., Ambrose E.J. 1976; Autoradiographic studies of M. leprae. Leprosy Review 47:267–273
    [Google Scholar]
  7. Khanolkar S.R., Ambrose E.J., Chulawalla R.G., Bapat C.V. 1978; Autoradiographic and metabolic studies of M. leprae. Leprosy Review 49:187–198
    [Google Scholar]
  8. Makino N.P., Mcmahill P., Mason H.S. 1974; The oxidation state of copper in resting tyrosinase. Journal of Biological Chemistry 249:6062–6066
    [Google Scholar]
  9. Prabhakaran K., Kirchheimer W.R. 1966; Use of 3,4-dihydroxyphenylalanine oxidation in the identification of Mycobacterium leprae. Journal of Bacteriology 92:1267–1268
    [Google Scholar]
  10. Prabhakaran K., Harris E.B., Kirchheimer W.F. 1973; Particulate nature of o-% diphenoloxidase in M. leprae and assay of the enzyme by the radioisotope technique. Microbios 8:151–157
    [Google Scholar]
  11. Prabhakaran K., Harris E.B., Kirchheimer W.F. 1975; o-Diphenoloxidase of Mycobacterium leprae separated from infected armadillo tissues. Infection and Immunity 12:267–269
    [Google Scholar]
  12. Prabhakaran K., Harris E.B., Kirchheimer W.F. 1976; Binding of 14C-labelled DOPA by M. leprae in vitro. International Journal of Leprosy 44:58–64
    [Google Scholar]
  13. Wheeler P.R., Draper P. 1980; Soluble blue as a counter stain in the Ziehl-Neelsen procedure. International Journal of Leprosy 48:15–17
    [Google Scholar]
  14. WORLD HEALTH ORGANIZATION 1976 Report of the Second IMMLEP Task Force Meeting, 1-5 December 1975. Reprinted in Leprosy Review 47:313–332
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-127-2-385
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error