Dynamics of Growth Control in a Marine Yeast Subjected to Perturbation
Stebbing, A. R. D. and Norton, J. P. and Brinsley, M. D.,, 130, 1799-1808 (1984),
doi = https://doi.org/10.1099/00221287-130-7-1799,
publicationName = Microbiology Society,
issn = 1350-0872,
abstract= Normalized specific growth rates of cultures of the yeast Rhodotorula rubra apparently indicate the activity of a growth control mechanism, when growth is perturbed with low concentrations of a toxic inhibitor (cadmium). Data from a number of experiments, in which different cadmium concentrations were used, indicate non-linear growth control dynamics and some features of a model structure, but do not permit it to be defined. Interpretation of the oscillatory behaviour as the response of a control mechanism to perturbation suggests that inhibition of mean growth rates, indicated by a threshold on dose-response curves, is due to overloading of the control mechanism or 'saturation'. Hormesis, the tendency of subinhibitory levels of typically toxic agents to stimulate growth, is a consequence of transient or sustained overcorrections by the control mechanism to low levels of an inhibitory stimulus.,
language=,
type=