Glutamine Cycling in Neurospora crassa Calderón, Jorge and Mora, Jaime,, 131, 3237-3242 (1985), doi = https://doi.org/10.1099/00221287-131-12-3237, publicationName = Microbiology Society, issn = 1350-0872, abstract= Summary: The accumulation of amino acids and the excretion of ammonium have been studied in various Neurospora crassa ammonium assimilation mutants, together with the labelling of glutamine in the presence of [U-14C]sucrose when N. crassa grows on glutamine as the nitrogen source. Ammonium coming from glutamine degradation by the ω-amidase pathway is assimilated by NADP-dependent glutamate dehydrogenase and glutamine synthetase. The operation of these enzymes results in a cycling of glutamine that seems to be essential for cell growth. In addition, glutamine is also converted to glutamate by glutamate synthase., language=, type=