Regulation of Salmonella typhimurium pyr Gene Expression: Effect of Changing Both Purine and Pyrimidine Nucleotide Pools

References

1. Abdelal A.T.H., Ingraham J.L. 1975; Carbamylphosphate synthetase fromSalmonella typhimurium. . Journal of Biological Chemistry 250:4410–4417
   [Google Scholar]
2. Bonekamp F., Clemmesen K., Karlström O., Jensen K.F. 1984; Mechanism of UTP-modu-lated attenuation at the pyrE gene of Escherichia coli:an example of operon polarity control through the coupling between translation and transcription. EMBO Journal 3:2857–2861
   [Google Scholar]
3. Bouvier J., Patte J.-C., Stragier P. 1984; Multiple regulatory signals in the control region of theEscherichia coli carAB operon. Proceedings of the National Academy of Sciences of the United States of America 81:4139–4143
   [Google Scholar]
4. Clark D.J., Maaløe O. 1967; DNA replication and the division cycle ofEscherichia coli. . Journal of Molecular Biology 23:99–112
   [Google Scholar]
5. Clemmesen K., Bonekamp F., Karlstrøm O., Jensen K.F. 1985; Role of translation in the UTP-modulated attenuation at thepyrBI gene of Escherichia coli. . Molecular and General Genetics 201:247–251
   [Google Scholar]
6. Edlin G., Maaløe O. 1966; Synthesis and breakdown of mRNA without protein synthesis. Journal of Molecular Biology 15:428–434
   [Google Scholar]
7. Gerhart J.C., Pardee A.B. 1962; The enzymology of control of feedback inhibition. Journal of Biological Chemistry 237:891–896
   [Google Scholar]
8. Hoffmeyer J., Neuhard J. 1971; Metabolism of exogenous purine bases and nucleosides bySalmonella typhimurium. . Journal of Bacteriology 106:14–24
   [Google Scholar]
9. Jensen K.F. 1979; Apparent involvement of purines in the control of expression ofSalmonella typhimurium pyr genes: analysis of a leaky guaB mutant resistant to pyrimidine analogs. Journal of Bacteriology 138:731–738
   [Google Scholar]
10. Jensen K.F., Houlberg U., Nygaard P. 1979; Thin-layer chromatographic methods to isolate ³²P-labeled 5-phosphoribosyl-α-1 -pyrophosphate (PRPP): determination of cellular PRPP pools and assay of PRPP synthetase. Analytical Biochemistry 98:254–263
    [Google Scholar]
11. Jensen K.F., Neuhard J., Schack L. 1982; RNA polymerase involvement in the regulation ofSalmonella typhimurium pyr genes. Isolation of a fluorouracil-resistant mutant with high, constitutive expression of pyrB and pyrE genes due to a mutation in rpoBC. . EMBO Journal 1:69–74
    [Google Scholar]
12. Jensen K.F., Larsen J.N., Schack L., Sivertsen A. 1984; Studies on the structure and expression ofEscherichia coli pyrC, pyrD and pyrF using the cloned genes. European Journal of Biochemistry 140:343–352
    [Google Scholar]
13. Jensen K. F., Bonekamp F., Poulsen P. 1986a; Attenuation at nucleotide biosynthetic genes and amino acid biosynthetic operons of Escherichia coli. . Trends in Biochemical Sciences 11:362–365
    [Google Scholar]
14. Jensen K.F., Fast R., Karlstrøm O., Larsen J.N. 1986b; Association of RNA polymerase having increasedK_m for ATP and UTP with hyperexpression of the pyrB and pyrE genes of Salmonella typhimurium. . Journal of Bacteriology 166:857–865
    [Google Scholar]
15. Kelln R.A., Neuhard J. 1988; Regulation ofpyrC expression in Salmonella typhimurium: identification of a regulatory region. Molecular and General Genetics 212:287–294
    [Google Scholar]
16. Kelln R.A., Kinahan J.J., Foltermann K.F., O’Donovan J.R. 1975; Pyrimidine biosynthetic enzymes ofSalmonella typhimurium, repressed by growth in the presence of cytidine. Journal of Bacteriology 124:764–774
    [Google Scholar]
17. Kilstrup M., Lu C.-D., Abdelal A., Neuhard J. 1988; Nucleotide sequence of thecar A gene and regulation of the carAB operon in Salmonella typhimurium. . European Journal of Biochemistry 175:587–593
    [Google Scholar]
18. Kingston R.E., Nierman W.C., Chamberlin M. 1981; A direct effect of guanosine tetraphosphate on pausing ofEscherichia coli RNA polymerase during RNA chain elongation. Journal of Biological Chemistry 256:2787–2797
    [Google Scholar]
19. Kornberg A., Horecker B.L. 1955; Glucose-6-phosphate dehydrogenase. Methods in Enzymology 1:323–326
    [Google Scholar]
20. Larsen J.N., Jensen K.F. 1985; Nucleotide sequence of thepyrD gene of Escherichia coli and characterization of the flavoprotein dihydroorotate dehydrogenase. European Journal of Biochemistry 151:59–65
    [Google Scholar]
21. Michaels G., Kelln R.A., Narang F.E. 1987; Cloning, nucleotide sequence and expression of thepyrBI operon of Salmonella typhimurium. . European Journal of Biochemistry 166:55–61
    [Google Scholar]
22. Miller J. H. 1972 Experiments in Molecular Genetics. Cold Spring Harbor, NY:: Cold Spring Harbor Laboratory.;
    [Google Scholar]
23. Neuhard J., Jensen K. F., Stauning E. 1982; Salmonella typhimurium mutants with altered expression of the pyrA gene due to changes in RNA polymerase. EMBO Journal 1:1141–1149
    [Google Scholar]
24. Neuhard J., Stauning E., Kelln R.A. 1985; Cloning and characterization of thepyrE gene and of pyrE:: Mud 1 (Aplac) fusions from Salmonella typhimurium. . European Journal of Biochemistry 146:597–603
    [Google Scholar]
25. Neuhard J., Kelln R.A., Stauning E. 1986; Cloning and characterization of theSalmonella typhimurium pyrC gene encoding dihydroorotase. European Journal of Biochemistry 157:335–342
    [Google Scholar]
26. Poulsen P., Jensen K.F. 1987; Effect of UTP and GTP pools on attenuation at thepyrE gene of Escherichia coli. . Molecular and General Genetics 208:152–158
    [Google Scholar]
27. Poulsen P., Jensen K.F., Valentin-Hansen P., Carlsson P., Lundberg L.G. 1983; Nucleotide sequence of theEscherichia coli pyrE gene and of the DNA in front of the protein-coding region. European Journal of Biochemistry 135:1783–1790
    [Google Scholar]
28. Poulsen P., Bonekamp F., Jensen K.F. 1984; Structure of theEscherichia coli pyrE operon and control of pyrE expression by a UTP-modulated intercistronic attenuation. EMBO Journal 3:1783–1790
    [Google Scholar]
29. Roland K.L., Powell F.E., Turnbough C.L. Jr 1985; Role of translation and attenuation in the control ofpyrBI operon expression in Escherichia coliK-12. Journal of Bacteriology 163:991–999
    [Google Scholar]
30. Schwartz M., Neuhard J. 1975; Control of expression of thepyr genes in Salmonella typhimurium: effects of variations in uridine and cytidine nucleotide pools. Journal of Bacteriology 121:814–822
    [Google Scholar]
31. Turnbough C.L. Jr 1983; Regulation ofEscherichia coli aspartate transcarbamylase synthesis by guanosine tetraphosphate and pyrimidine ribo-nucleoside triphosphates. Journal of Bacteriology 153:998–1007
    [Google Scholar]
32. Turnbough C.L. Jr Hicks H.L., Donahue J.P. 1983; Attenuation control ofpyrBI operon expression in Escherichia coli K12. Proceedings of the National Academy of Sciences of the United States of America 80:368–372
    [Google Scholar]