Catabolism of 3- and 4-hydroxyphenylacetic acid by Klebsiella pneumoniae
Martín, Margarita and Gibello, Alicia and Fernández, Javier and Ferrer, Estrella and Garrido-Pertierra, Amando,, 137, 621-628 (1991),
doi = https://doi.org/10.1099/00221287-137-3-621,
publicationName = Microbiology Society,
issn = 1350-0872,
abstract= Klebsiella pneumoniae catabolizes both 4-hydroxyphenylacetic acid and 3-hydroxyphenylacetic acid via meta-cleavage of 3,4-dihydroxyphenylacetic acid, ultimately yielding pyruvate and succinate. The organism can synthesize two hydroxylases catalysing 3,4-dihydroxyphenylacetic acid formation, which differ in substrte specificity, cofactor requirement, kinetics and regulation. Five enzymes sequentially involved in the catabolism of 3,4-dihydroxyphenylacetic acid are encoded on a 7 kbp fragment of the K. pneumoniae chromosome that has been isolated in a recombinant plasmid.,
language=,
type=