RT Journal Article SR Electronic(1) A1 Martín, Margarita A1 Gibello, Alicia A1 Fernández, Javier A1 Ferrer, Estrella A1 Garrido-Pertierra, AmandoYR 1991 T1 Catabolism of 3- and 4-hydroxyphenylacetic acid by Klebsiella pneumoniae JF Microbiology, VO 137 IS 3 SP 621 OP 628 DO https://doi.org/10.1099/00221287-137-3-621 PB Microbiology Society, SN 1465-2080, AB Klebsiella pneumoniae catabolizes both 4-hydroxyphenylacetic acid and 3-hydroxyphenylacetic acid via meta-cleavage of 3,4-dihydroxyphenylacetic acid, ultimately yielding pyruvate and succinate. The organism can synthesize two hydroxylases catalysing 3,4-dihydroxyphenylacetic acid formation, which differ in substrte specificity, cofactor requirement, kinetics and regulation. Five enzymes sequentially involved in the catabolism of 3,4-dihydroxyphenylacetic acid are encoded on a 7 kbp fragment of the K. pneumoniae chromosome that has been isolated in a recombinant plasmid., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-137-3-621