Characterization of a ß-lactamase produced by Pseudomonas paucimobilis
Corkill, John E. and Hart, Charles A. and McLennan, Alexander G. and Aspinall, Stephen,, 137, 1425-1429 (1991),
doi = https://doi.org/10.1099/00221287-137-6-1425,
publicationName = Microbiology Society,
issn = 1350-0872,
abstract= Summary: A novel β-lactamase enzyme produced by a strain of Pseudomonas paucimobilis is described. The enzyme differs from other recorded β-lactamases from Gram-negative aerobic bacteria. It was constitutive, and had the characteristics of a penicillinase. One single band of β-lactamase activity at pI 4.6 was seen on iso-electric focusing. The enzyme had a molecular mass of 30 kDa. The β-lactamase was strongly inhibited by tazobactam, sulbactam and clavulanic acid but not by the thiol residue inhibitors p-chloromercuribenzoate and p-chloromercuriphenylsulphonic acid, or by metallo-enzyme inhibitors. Plasmid DNA was not demonstrable, suggesting that the enzyme was chromosomally encoded.,
language=,
type=