@article{mbs:/content/journal/micro/10.1099/00221287-139-1-153, author = "Woodward, S. and Sultan, H. Y. and Barrett, D. K. and Pearce, R. B.", title = "Two new antifungal metabolites produced by Sparassis crispa in culture and in decayed trees", journal= "Microbiology", year = "1993", volume = "139", number = "1", pages = "153-159", doi = "https://doi.org/10.1099/00221287-139-1-153", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-139-1-153", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "The basidiomycete fungus Sparassis crispa produced three antifungal compounds during submerged culture in 2% malt broth. One compound appeared to be sparassol (methyl-2-hydroxy-4-methoxy-6-methylbenzoate), first characterized in 1924. The other two, termed ScI and ScII, exhibited considerably greater antifungal activity than did sparassol against Cladosporium cucumerinum, and were characterized as methyl-2,4-dihydroxy-6-methylbenzoate (methyl orsellinate) and an incompletely determined methyl-dihydroxy-methoxy-methylbenzoate, respectively. Both compounds were found in the decayed wood of trees, where their presence was diagnostic of S. crispa infection. The possible ecological role of these compounds is discussed.", }