@article{mbs:/content/journal/micro/10.1099/00221287-143-6-2079, author = "Chen, C. F. and Lan, J. and Korovine, M. and Shao, Z. Q. and Tao, L. and Zhang, J. and Newman, E. B.", title = "Metabolic regulation of Irp gene expression in Escherichia coli K-12", journal= "Microbiology", year = "1997", volume = "143", number = "6", pages = "2079-2084", doi = "https://doi.org/10.1099/00221287-143-6-2079", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-143-6-2079", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", keywords = "Escherichia coli", keywords = "metabolism", keywords = "regulation of lrp expression", keywords = "leucine-responsive regulatory protein", abstract = "Expression of the Irp gene is regulated in part by the nutrients available to the cell, and is decreased in rich medium, in glucose minimal media enriched with amino acids, and in minimal medium with alternative carbon sources, such as acetate and succinate. When Lrp production is increased in a given medium, expression of its target genes is also increased. However, when the medium is changed from glucose to acetate, the response of the target genes is governed by many factors.", }