1887

Abstract

The fission yeast shows bipolar growth and is a convenient model for studying cell polarity and polar growth. This paper shows that the related var. can switch to unipolar growth and can exist in both yeast and mycelial phases. On solid media, the yeast phase is unstable and prone to switch to the mycelial form, which shows unipolar growth by tip elongation. The hyphae can colonize the body of the substrate (true mycelium) or just its surface (pseudo-mycelium). The yeast-to-mycelium transition and the growth of the mycelium are regulated by a nutritional gradient and are associated with extensive vacuolation. The mycelium can convert into arthroconidia or return to the yeast phase in response to environmental changes. These environmentally controlled morphological transitions make var. an attractive model for the investigation of cell polarity and morphogenesis.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-144-5-1319
1998-05-01
2024-03-29
Loading full text...

Full text loading...

/deliver/fulltext/micro/144/5/mic-144-5-1319.html?itemId=/content/journal/micro/10.1099/00221287-144-5-1319&mimeType=html&fmt=ahah

References

  1. Alfa, C., Fantes, P., Hyams, J., Mcleod, M., Warbrick, E. (1993) Experiments with Fission Yeasts. Cold Spring Harbor, NY:: Cold Spring Harbor Laboratory;
    [Google Scholar]
  2. Bartnicki-Garcia, S. (1963); Mold—yeast dimorphism of Mucor rouxii.. Bacteriological Reviews 27:(3)293–304 [View Article]
    [Google Scholar]
  3. Cole, G. T. (1975); The thallic mode of conidiogenesis in the Fungi Imperfecti.. Cam J Bot 53:(24)2983–3001 [View Article]
    [Google Scholar]
  4. Cole, G. T., Samson, R. A. (1983) Conidium and conidiospore formation in pathogenic microfungi.. Edited by Howard, D. H. Fungi Pathogenic for Humans and Animals, Part A, Biology. New York & Basel:: Marcel Dekker,;437–524
    [Google Scholar]
  5. Garrison, R. G. (1983) Ultrastructural cytology of pathogenic fungi.. Edited by Howard, D. H. Fungi Pathogenic for Humans and Animals, Part A, Biology. New York & Basel:: Marcel Dekker,;229–321
    [Google Scholar]
  6. Gimeno, C. J., Ljungdahl, P. O., Style, C. A., Fink, G. R. (1992); Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: regulation of starvation and RAS.. Cell 68:(6)1077–1090 [View Article]
    [Google Scholar]
  7. Gow, N. A. R., Gooday, G. W. (1982); Vacuolation, branch production and linear growth of germ tubes of Candida albicans.. Journal of General Microbiology 128:2195–2198
    [Google Scholar]
  8. Gow, N. A. R., Gooday, G. W. (1987); Cytological aspects of dimorphism in Candida albicans.. Crc Critical Reviews in Microbiology 15:(1)73–78 [View Article]
    [Google Scholar]
  9. Guevara-Olvera, L., Calvo-Mendez, C., Ruiz-Herrera J. (1993); The role of polyamine metabolism in dimorphism of Yarrowia lipolytica.. Journal of General Microbiology 139:(3)485–493 [View Article]
    [Google Scholar]
  10. Hagan, I. M., Hyams, J. S. (1988); The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Scbizosaccbaromyces pombe.. ] Cell Sci 89:343–357
    [Google Scholar]
  11. Hill, K. L., Catlett, N. L., Weisman, L. S. (1996); Actin and myosin function in directed vacuole movement during cell division in Saccharomyces cerevisiae.. Journal of Cell Biology 135:(6)1535–1549 [View Article]
    [Google Scholar]
  12. Johnson, B. F., Calleja, G. B., Boisclair, I., Yoo, B. Y. (1979); Cell division in yeasts. III. The biassed, asymmetric location of the septum in the fission yeast cell, Schizosaccharomyces pombe.. Experimental Cell Research 123:(2)253–259 [View Article]
    [Google Scholar]
  13. Johnson, B. F., Calleja, G. B., Yoo, B. Y., Zuker, M., McDonald, I. J. (1982); Cell division: key to cellular morphogenesis in the fission yeast.. Schizosaccharomyces Survey of Cell Biology 75:167–208
    [Google Scholar]
  14. Kobayashi, G. S., Medoff, G., Maresca, B., Sacco, M., Kumar, B. V. (1985) Studies on phase transition in the dimorphic pathogen Histoplasma capsulatum.. Edited by Szaniszlo, P. J. Fungal Dimorphism, with Emphasis on Fungi Pathogenic for Humans. New York:: Plenum,;69–91
    [Google Scholar]
  15. Levin, D. E., Errede, B. (1995); The proliferation of MAP kinase signalling pathways in yeast.. Current Biology 7:(2)197–202 [View Article]
    [Google Scholar]
  16. Marks, J., Hyams, J. S. (1985); Localization of F-actin through the cell division cycle of Schizosaccharomyces pombe.. European Journal of Cell Biology 39:27–32
    [Google Scholar]
  17. May, J. W., Mitchison, J. M. (1995); Pattern of polar extension of the cell wall in the fission yeast Schizosaccharomyces pombe.. Canadian Journal of Microbiology 41:(3)273–277 [View Article]
    [Google Scholar]
  18. Mitchison, J. M. (1970); Physiological and cytological methods for Schizosaccharomyces pombe.. Methods Cell Physiol 4:131–165
    [Google Scholar]
  19. Mitchison, J. M., Nurse, P., Miyata, H., Miyata, M., Johnson, B. F. (1985); Growth in cell length in the fission yeast Schizosaccharomyces pombe, Patterns of extension growth of the fission yeast, Schizosaccharomyces pombe.. Journal of Cell Science 75:357–376 1986
    [Google Scholar]
  20. Miyata, H., Miyata, M., Johnson, B. F. (1990); Pattern of end growth of the fission yeast Schizosaccharomyces pombe.. Canadian Journal of Microbiology 36:(6)390–394 [View Article]
    [Google Scholar]
  21. Moreno, S., Klar, A., Nurse, P. (1991); Molecular genetic analysis of fission yeast Schizosaccharomyces pombe.. Methods in Enzymology, Vol 46: Research on Nitrification and Related Processes, Pt B. 194:795–823
    [Google Scholar]
  22. Radford, D. R., Challacombe, S. J., Walter, J. D. (1997); Scanning electron microscopy of the development of structured aerial mycelia and satellite colonies of phenotypically switched Candida albicans.. Journal of Medical Microbiology 46:(4)326–332 [View Article]
    [Google Scholar]
  23. Robson, G. D., Prebble, E., Rickers, A., Hosking, S., Denning, D. W. et al. (1996); Polarized growth of fungal hyphae is defined by an alkaline pH gradient.. Fungal Genetics and Biology 20:(4)289–298 [View Article]
    [Google Scholar]
  24. Ruiz-Herrera, J., Leon, C. G., Guevara-Olvera, L., Carabez-Trejo, A. (1995); Yeast-mycelial dimorphism of haploid and diploid strains of Ustilago maydis.. Microbiology 141:(3)695–703 [View Article]
    [Google Scholar]
  25. San-Bias, F., San-Bias, G. (1985) Paracoccidoides brasiliensis.. Edited by Szaniszlo, P. J. Fungal Dimorphism With Emphasis on Fungi Pathogenic for Humans. New York:: Plenum,;93–120
    [Google Scholar]
  26. Sherwood-Higham, J.„ Zhu, Devine, W.-Y., C., A., Gooday, G. W., Gow, N. A. R., Gregory, D. W. (1994); Helical growth of hyphae of Candida albicans.. Journal of Medical and Veterinary Mycology 32:(6)437–445 [View Article]
    [Google Scholar]
  27. Sipiczki, M. (1995); Phylogenesis of fission yeasts. Contradictions surrounding the origin of a century old genus.. Antonie Leeuwenhoek 68:(2)119–149 [View Article]
    [Google Scholar]
  28. Sipiczki, M., Ferenczy, L. (1977); Protoplast fusion of Schizosaccharomyces pombe auxotrophic mutants of identical mating- type.. Molecular & General Genetics 151:(1)77–81 [View Article]
    [Google Scholar]
  29. Sipiczki, M., Grallert, A. (1997); Polarity, spatial organisation of cytoskeleton, and nuclear division in morphologically altered cells of Schizosaccharomyces pombe.. Can ] Microbiol 43:(11)991–998 [View Article]
    [Google Scholar]
  30. Sipiczki, M., Kucsera, J., Ulaszevski, S., Zsolt, J. (1982); Hybridization studies by crossing and protoplast fusion within the genus Schizosaccharomyces Lindner.. Journal of General Microbiology 128:1989–2000
    [Google Scholar]
  31. Sipiczki, M., Grallert, B., Miklos, I. (1993); Mycelial and syncytial growth in Schizosaccharomyces pombe induced by novel septation mutations.. Journal of Cell Science 104:485–493
    [Google Scholar]
  32. Snell, V., Nurse, P. (1993); Investigations into the control of cell form and polarity: the use of morphological mutants in fission yeast.. Development 1993 Supplement 289—299.
  33. Soli, D. R. (1985) Candida albicans.. Edited by Szaniszlo, P. J. Fungal Dimorphism with Emphasis on Fungi Pathogenic for Humans. New York:: Plenum,;167–195
    [Google Scholar]
  34. Tekeuchi, Y., Schmid, J., Caldwell, J. H., Harold, F. (1988); Transcellular ion currents and extension of Neurospora crassa.. J Membr Biol 101:(1)33–41 [View Article]
    [Google Scholar]
  35. van der Walt, J. P., Yarrow, D. (1984) Methods for the isolation, maintenance, classification and identification of yeasts.. Edited by Kreger-van Rij, N. J. W. The Yeasts. A Taxonomic Study. Amsterdam:: Elsevier,;45–104
    [Google Scholar]
  36. Weisman, L. S., Wickner, W. T. (1988); Intervacuolar exchange in the yeast zygote: a new pathway in organelle communication.. Science 241:(4865)589–591 [View Article]
    [Google Scholar]
  37. Wickes, B. L., Mayorga, M. E., Edman, U., Edman, J. C. (1996); Dimorphism and haploid fruiting in Cryptococcus neoformans: association with the a-mating type.. Proc Natl Acad Sci USA 93:(14)7327–7331 [View Article]
    [Google Scholar]
  38. Yamaguchi, M., Miyatsu, Y., Horikawa, Y., Sugahara, K., Mizo-,, Kawase, H., kami H., Kawase M., Tanake, H. (1994); Dynamics of hepatitis B virus core antigen in a transformed yeast cell: analysis with an inducible system.. Journal of Electron Microscopy 43:386–393
    [Google Scholar]
  39. Yarrow, D. (1984) Schizosaccharomyces Lindner.. Edited by Kreger-van Rij, N. J. W. The Yeasts. A Taxonomic Study. Amsterdam:: Elsevier,;414–422
    [Google Scholar]
  40. Yokoyama, K., Takeo, K. (1983); Differences of asymmetrical division between the pseudomycelial and yeast forms of Candida albicans and their effect on multiplication.. Archives of Microbiology 134:(3)251–253 [View Article]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-144-5-1319
Loading
/content/journal/micro/10.1099/00221287-144-5-1319
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error