@article{mbs:/content/journal/micro/10.1099/00221287-84-1-199, author = "Hedges, R. W. and Jacob, A. E. and Smith, J. T.", title = "Properties of an R Factor from Bordetella bronchiseptica", journal= "Microbiology", year = "1974", volume = "84", number = "1", pages = "199-204", doi = "https://doi.org/10.1099/00221287-84-1-199", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-84-1-199", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "SUMMARY: R906, a plasmid derived from a wild strain of Bordetella bronchiseptica, was transferred to Escherichia coli k12. In this host it is stably heritable, replicating as a DNA molecule with a molecular weight of 34.6 megadaltons. There are approximately three copies of the plasmid per chromosome. It is a member of compatibility group P. In E. coli, 906 confers resistance to ampicillin, streptomycin, sulphonamides and mercury salts. Resistance to ampicillin is determined by an oxacillin-hydrolysing β-lactamase whereas the resistance to streptomycin is not determined by either of the previously described streptomycin-inactivating enzymes but by some other mechanism.", }