RT Journal Article SR Electronic(1) A1 Gordon, Stephen V. A1 Parish, TanyaYR 2018 T1 Microbe Profile: Mycobacterium tuberculosis: Humanity's deadly microbial foe JF Microbiology, VO 164 IS 4 SP 437 OP 439 DO https://doi.org/10.1099/mic.0.000601 PB Microbiology Society, SN 1465-2080, AB Mycobacterium tuberculosis is an expert and deadly pathogen, causing the disease tuberculosis (TB) in humans. It has several notable features: the ability to enter non-replicating states for long periods and cause latent infection; metabolic remodelling during chronic infection; a thick, waxy cell wall; slow growth rate in culture; and intrinsic drug resistance and antibiotic tolerance. As a pathogen, M. tuberculosis has a complex relationship with its host, is able to replicate inside macrophages, and expresses diverse immunomodulatory molecules. M. tuberculosis currently causes over 1.8 million deaths a year, making it the world’s most deadly human pathogen., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.000601