1887

Abstract

Mutants of unable to participate in vegetative hyphal fusion (anastomosis) were isolated and characterized. From this analysis, three genes, , and , were identified and shown to be required for hyphal fusion. The and genes are homologues of the and genes, which encode a dimeric transcription factor in yeast. We demonstrate that in the and genes are required for hyphal fusion and normal hyphal morphology, and influence both asexual and sexual development. The gene encodes a 1686 amino acid protein with two putative WD40 domains, which might participate in protein–protein interactions. deletion mutants had a reduced rate of hyphal extension and altered hyphal morphology, and were unable to produce the conidial anastomosis tubes that are required for hyphal fusion during colony initiation.

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2010-09-01
2024-03-29
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