RT Journal Article SR Electronic(1) A1 Jernberg, Cecilia A1 Löfmark, Sonja A1 Edlund, Charlotta A1 Jansson, Janet K.YR 2010 T1 Long-term impacts of antibiotic exposure on the human intestinal microbiota JF Microbiology, VO 156 IS 11 SP 3216 OP 3223 DO https://doi.org/10.1099/mic.0.040618-0 PB Microbiology Society, SN 1465-2080, AB Although it is known that antibiotics have short-term impacts on the human microbiome, recent evidence demonstrates that the impacts of some antibiotics remain for extended periods of time. In addition, antibiotic-resistant strains can persist in the human host environment in the absence of selective pressure. Both molecular- and cultivation-based approaches have revealed ecological disturbances in the microbiota after antibiotic administration, in particular for specific members of the bacterial community that are susceptible or alternatively resistant to the antibiotic in question. A disturbing consequence of antibiotic treatment has been the long-term persistence of antibiotic resistance genes, for example in the human gut. These data warrant use of prudence in the administration of antibiotics that could aggravate the growing battle with emerging antibiotic-resistant pathogenic strains., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.040618-0