RT Journal Article SR Electronic(1) A1 Kjos, Morten A1 Borrero, Juan A1 Opsata, Mona A1 Birri, Dagim J. A1 Holo, Helge A1 Cintas, Luis M. A1 Snipen, Lars A1 Hernández, Pablo E. A1 Nes, Ingolf F. A1 Diep, Dzung B.YR 2011 T1 Target recognition, resistance, immunity and genome mining of class II bacteriocins from Gram-positive bacteria JF Microbiology, VO 157 IS 12 SP 3256 OP 3267 DO https://doi.org/10.1099/mic.0.052571-0 PB Microbiology Society, SN 1465-2080, AB Due to their very potent antimicrobial activity against diverse food-spoiling bacteria and pathogens and their favourable biochemical properties, peptide bacteriocins from Gram-positive bacteria have long been considered promising for applications in food preservation or medical treatment. To take advantage of bacteriocins in different applications, it is crucial to have detailed knowledge on the molecular mechanisms by which these peptides recognize and kill target cells, how producer cells protect themselves from their own bacteriocin (self-immunity) and how target cells may develop resistance. In this review we discuss some important recent progress in these areas for the non-lantibiotic (class II) bacteriocins. We also discuss some examples of how the current wealth of genome sequences provides an invaluable source in the search for novel class II bacteriocins., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.052571-0