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Volume 158, Issue 10

Genomics of alternative sulfur utilization in ascomycetous yeasts Free

Abstract

Thirteen ascomycetous yeast strains with sequenced genomes were assayed for their ability to grow on chemically defined medium with 16 different sulfur compounds as the only significant source of sulfur. These compounds included sulfoxides, sulfones, sulfonates, sulfamates and sulfate esters. Broad utilization of alternative sulfur sources was observed in (syn. ), , (syn. ), , (syn. ), , (syn. ) and . , and were mainly able to utilize sulfonates and sulfate esters, while and were limited to aromatic sulfate esters. Genome analysis identified several candidate genes with bacterial homologues that had been previously shown to be involved in the utilization of alternative sulfur sources. Analysis of candidate gene promoter sequences revealed a significant overrepresentation of DNA motifs that have been shown to regulate sulfur metabolism in .

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2012-10-01
2024-04-19
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Genomics of alternative sulfur utilization in ascomycetous yeasts
Microbiology 158, 2585 (2012); https://doi.org/10.1099/mic.0.060285-0
/content/journal/micro/10.1099/mic.0.060285-0
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