1887

Abstract

Screening of the genome sequence of the strain Agy99 from Ghana with tandem repeats finder software revealed 34 novel non-degenerate tandem repeats containing loci suitable for variable number tandem repeats (VNTR) typing. All loci revealed polymorphism within isolates of geographically diverse origins. The results confirm the evolutionary scenario suggested by multi-locus sequence typing in which a progenitor of all lineages emerged from the environmental species and subsequently diverged into several geographical lineages. For further attempts to develop a VNTR-based genetic fingerprinting tool for , it is suggested that the focus should rather be on than on the African Agy99 genome sequence as a starting point.

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2007-05-01
2024-03-28
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