Biochemistry of methanogenesis: a tribute to Marjory Stephenson:1998 Marjory Stephenson Prize Lecture

References

1. Abken H.-J., Deppenmeier U. 1997; Purification and proper- ties of an F₄₂₀H₂ dehydrogenase from Methanosarcina mazei Göl.. FEMS Microbiol Lett 154:231–237
   [Google Scholar]
2. Abken H.-J., Tietze M., Brodersen J., Bäumer S., Beifuss U., Deppenmeier U. 1998a; Isolation and characterization of methanophenazine and function of phenazines in membrane- bound electron transport ofMethanosarcina mazei Gol.. J Bacteriol 180:2027–2032
   [Google Scholar]
3. Abken H.-J., Bäumer S., Broderson J., Murakami E., Ragsdale S.W., Gott&halk G., Deppenmeier U. 1998b; Membrane- bound electron transport and H⁺-translocation inMethanosarcina mazei Gol.. BlOspectrum Sonderausgabe 38:
   [Google Scholar]
4. Afting C., Hochheimer A., Thauer R.K. 1998; Function of Informing methylenetetrahydromethanopterin dehydrogenase fromMethanobacterium thermoautotrophicum in coenzyme F₄₂₀ reduction with H₂.. Arch Microbiol 169:206–210
   [Google Scholar]
5. Ahn Y., Krzycki J.A., Floss H.G. 1991; Steric course of the reduction of ethyl coenzyme M to ethane catalyzed by methyl coenzyme M reductase fromMethanosarcina barkeri.. J Am Chem Soc 113:4700–4701
   [Google Scholar]
6. Albracht S.P.J. 1994; Nickel hydrogenases: in search of the active site.. Biochim Biophys Acta 1188:167–204
   [Google Scholar]
7. Albracht S.P.J., Graf E.-G., Thauer R.K. 1982; The EPR properties of nickel in hydrogenase fromMethanobacterium thermoautotrophicum.. FEBS Lett 140:311–313
   [Google Scholar]
8. Albracht S.P.J., Ankel-Fuchs D., van der Zwaan J.W., Fontijn R.D., Thauer R.K. 1986; A new EPR signal of nickel inMethanobacterium thermoautotrophicum.. Biochim Biophys Acta 870:50–57
   [Google Scholar]
9. Albracht S.P.J., Ankel-Fuchs D., Böcher R., Ellermann J., Moll J., van der Zwaan J.W., Thauer R.K. 1988; Five new EPR signals assigned to nickel in methyl-coenzyme M reductase fromMethanobacterium thermoautotrophicum, strain Marburg.. Biochim Biophys Acta 955:86–102
   [Google Scholar]
10. Andrews S.C., Berks B.C., McClay J., Ambler A., Quail M.A., Golby P., Guest J.R. 1997; A 12-cistronE&herichia colioperon{hyf) encoding a putative proton-translocating formate hydrogenlyase system.. Microbiology 143:3633–3647
    [Google Scholar]
11. Ankel-Fuchs D., Thauer R.K. 1986; Methane formation from methyl-coenzyme M in a system containing methyl-coenzyme M reductase, component B and reduced cobalamin.. Eur J Biochem 156:171–177
    [Google Scholar]
12. Asakawa S., Sauer K., Liesack W., Thauer R.K. 1998; Tetramethylammonium: coenzyme M methyltransferase system fromMethanococcoides species.. Arch Microbiol (in press)
    [Google Scholar]
13. Batch W.E., Wolfe R.S. 1979; Specificity and biological distribution of coenzyme M (2-mercaptoethanesulfonic acid).. J Bacteriol 137:256–263
    [Google Scholar]
14. Barker H.A. 1956 Bacterial Fermentations New York: Wiley;
    [Google Scholar]
15. Bäumer S., Murakami E., Brodersen J., Gott&halk G., Ragsdale S.W., Deppenmeier U. 1998; The F₄₂₀H₂: heterodisulfide oxidoreductase system fromMethanosarcina species. 2-Hydroxy- phenazine mediates electron transfer from F₄₂₀H₂ dehydrogenase to heterodisulfide reductase.. FEBS Lett 428:295–298
    [Google Scholar]
16. Becher B., Möller V. 1994; Ag_Na+ drives the synthesis of ATP via an △g_Na+-translocating F₄F₀ ATP synthase in membrane vesicles of the archaeonMethanosarcina mazei strain Göl.. J Bacteriol 176:2543–2550
    [Google Scholar]
17. Becher B., Müller V., Gott&halk G. 1992a; The methyl- tetrahydromethanopterin: coenzyme M methyltransferase ofMethanosarcina strain Göl is a primary sodium pump.. FEMS Microbiol Lett 91:239–244
    [Google Scholar]
18. Becher B., Muller V., Gott&halk G. 1992b; N⁵-methyl- tetrahydromethanopterin: coenzyme M methyltransferase ofMethanosarcina strain Gol is an Na⁺ translocating membrane protein.. J Bacteriol 174:7656–7660
    [Google Scholar]
19. Becker D.F., Ragsdale S.W. 1998; Activation of methyl- &oM reductase to high specific activity after treatment of whole cells with sodium sulfide.. Biochemistry 37:2639–2647
    [Google Scholar]
20. Berk H., Thauer R.K. 1997; Function of coenzyme F₄₂₀- dependent NADP reductase in methanogenic archaea containing an NADP-dependent alcohol dehydrogenase.. Arch Microbiol 168:396–402
    [Google Scholar]
21. Berk H., Buckel W., Thauer R.K., Frey P.A. 1996; Re-face stereospecificity at C4 of NAD(P) for alcohol dehydrogenase fromMethanogenium organophilum and for (R)-2-hydroxyglutarate dehydrogenase fromAcidaminococcus fermentans as determined by¹H-NMR spectro&opy.. FEBS Lett 399:92–94
    [Google Scholar]
22. Berkessel A. 1991; Methyl-coenzyme M reductase: model studies on pentadentate nickel complexes and a hypothetical mechanism.. Bioorg Chem 19:101–115
    [Google Scholar]
23. Berkessel A., Thauer R.K. 1995; On the mechanism of catalysis by a metal-free hydrogenase from methanogenic Archaea: enzymatic transformation of H₂ without a metal and its analogy to the chemistry of alkanes in superacidic solution.. Angew Chem Int Ed Engl 34:2247–2250
    [Google Scholar]
24. Bertram P.A., Thauer R.K. 1994; Thermodynamics of the formylmethanofuran dehydrogenase reaction inMethano- bacterium thermoautotrophicum.. Eur J Biochem 226:811–818
    [Google Scholar]
25. Bertram P.A., Karra&h M., &hmitz R.A., Böcher R., Albracht S.P.J., Thauer R.K. 1994a; Formylmethanofuran dehydrogenases from methanogenic Archaea. Substrate specificity, EPR properties and reversible inactivation by cyanide of the molybdenum or tungsten iron-sulfur proteins.. Eur J Biochem 220:477–484
    [Google Scholar]
26. Bertram P.A., &hmitz R.A., Linder D., Thauer R.K. 1994b; Tungstate can substitute for molybdate in sustaining growth ofMethanobacterium thermoautotrophicum: identification and characterization of a tungsten isoenzyme of formylmethanofuran dehydrogenase.. Arch Microbiol 161:220–228
    [Google Scholar]
27. Blaut M. 1994; Metabolism of methanogens.. Antonie Leeuwenhoek 66:187–208
    [Google Scholar]
28. Bobik T.A., Wolfe R.S. 1989; An unusual thiol-driven fumarate reductase in Methanobacterium with the production of the heterodisulfide of coenzyme M and N-(7-mercapto- heptanoyl)threonine-0³-phosphate.. J Biol Chem 264:18714–18718
    [Google Scholar]
29. Bobik T.A., Olson K.D., Noll K.M., Wolfe R.S. 1987; Evidence that the heterodisulfide of coenzyme M and 7-mercap- toheptanoylthreonine phosphate is a product of the methyl- reductase reaction inMethanobacterium.. Biochem Biophys Res Commun 149:455–460
    [Google Scholar]
30. Bokranz M., Klein A. 1987; Nucleotide sequence of the methyl-coenzyme M reductase gene cluster fromMethanosarcina barkeri.. Nucleic Acids Res 15:4350–4351
    [Google Scholar]
31. Bokranz M., Bäumner G., Allmansberger R., Ankel-Fuchs D., Klein A. 1988; Cloning and characterization of the methyl coenzyme M reductase genes fromMethanobacterium thermoautotrophicum.. J Bacteriol 170:568–577
    [Google Scholar]
32. Bonacker L.G., Baudner S., Thauer R.K. 1992; Differential expression of the two methyl-coenzyme M reductases inMethanobacterium thermoautotrophicum as determined immuno- chemically via isoenzyme-specific antisera.. Eur J Biochem 206:87–92
    [Google Scholar]
33. Bonacker L.G., Baudner S., Mör&hel E., Böcher R., Thauer R.K. 1993; Properties of the two isoenzymes of methyl-coenzyme M reductase inMethanobacterium thermoautotrophicum.. Eur J Biochem 217:587–595
    [Google Scholar]
34. Boone D.R., Whitman W.B., Rouvière P. 1993; Diversity and taxonomy of methanogens.. In Methanogenesis pp. 35–80 Ferry J.G., Bhattacharya SK. Edited by New York & London: Chapman & Hall;
    [Google Scholar]
35. Braks I.J., Hoppert M., Roge S., Mayer F. 1994; Structural aspects and immunolocalization of the F₄₂₀-reducing and non- F₄₂₀-reducing hydrogenases fromMethanobacterium thermo-autotrophicum Marburg.. J Bacteriol 176:7677–7687
    [Google Scholar]
36. Brenner M.C., Zhang H., &ott R.A. 1993; Nature of the low activity of S-methyl-coenzyme-M reductase as determined by active-site titrations.. J Biol Chem 268:18491–18495
    [Google Scholar]
37. Buckel W. 1996; Unusual dehydrations in anaerobic bacteria: considering ketyls (radical anions) as reactive intermediates in enzymatic reactions.. FEBS Lett 389:20–24
    [Google Scholar]
38. Buckel W., Keese R. 1995; One electron redox reactions of CoASH esters in anaerobic bacteria - a mechanistic proposal.. Angew Chem Int Ed Engl 34:1502–1506
    [Google Scholar]
39. Bult C.J., White O., Olsen G.J. & 37 other authors 1996; Complete genome sequence of the methanogenic archaeon,Methanococcus janna&hii.. &ience 273:1058–1073
    [Google Scholar]
40. Burke S.A., Krzycki J.A. 1995; Involvement of the “A” isozyme of methyltransferase II and the 29-kilodalton corrinoid protein in methanogenesis from monomethylamine.. J Bacteriol 177:4410–4416
    [Google Scholar]
41. Burke S.A., Krzycki J.A. 1997; Reconstitution of monomethylamine: coenzyme M methyl transfer with a corrinoid protein and two methyltransferases purified fromMethanosarcina barkeri.. J Biol Chem 272:16570–16577
    [Google Scholar]
42. Burke S.A., Lo S.L., Krzycki J.A. 1998; Clustered genes encoding the methyltransferases of methanogenesis from monomethylamine.. J Bacteriol 180:3432–3440
    [Google Scholar]
43. Burton G.W., Dobu T., Gabe E.J., Hughes I., Lee F.L., Prasad I., Ingold K.U. 1985; Autoxidation of biological molecules. 4. Maximizing the antioxidant activity of phenols.. J Am Chem Soc 107:7053–7065
    [Google Scholar]
44. Cammack R. 1997; The enzyme at the end of the food chain.. Nature 390:443–444
    [Google Scholar]
45. Cammack R., van Vliet P. 1998; Catalysis by nickel in biological systems.. In Bioinorganic Catalysis, 2nd edn.. Reedijk J., Bouwman E. Edited by (in press) New York: Marcel Dekker;
    [Google Scholar]
46. Chen W., Konisky J. 1993; Characterization of a membrane- associated ATPase fromMethanococcus voltae, a methanogenic member of the Archaea.. J Bacteriol 175:5677–5682
    [Google Scholar]
47. Chistoserdova L., Vorholt J.A., Thauer R.K., Lidstrom M.E. 1998; C₁ transfer enzymes and coenzymes linking methylo- trophic bacteria and methanogenic archaea.. &ience 281:99–102
    [Google Scholar]
48. Conrad R. 1996; Soil microorganisms as controllers of atmospheric trace gases (H₂, CO, CH₄, OCS, N₂O and NO).. Microbiol Rev 60:609–640
    [Google Scholar]
49. Cram D.S., Sherf B.A., Libby R.T., Mattaliano R.J., Rama-chandran K.L., Reeve J.N. 1987; Structure and expression of the genes,mcrBDCGA, which encode the subunits of component C of methyl coenzyme M reductase inMethanococcus vannielii.. Proc Natl Acad &i USA 84:3992–3996
    [Google Scholar]
50. Crane B.R., Siegel L.M., Getzoff E.D. 1995; Sulfite reductase structure at L6A: evolution and catalysis for reduction of inorganic anions.. &ience 270:59–67
    [Google Scholar]
51. Crane B.R., Siegel L.M., Getzoff E.D. 1997a; Structures of the siroheme- and Fe-4S-4-containing active center of sulfite reductase in different states of oxidation: heme activation via reduction-gated exogenous ligand exchange.. Biochemistry 36:12101–12119
    [Google Scholar]
52. Crane B.R., Siegel L.M., Getzoff E.D. 1997b; Probing the catalytic mechanism of sulfite reductase by X-ray crystallography: structures of theE&herichia coli hemoprotein in complex with substrates, inhibitors, intermediates, and products.. Biochemistry 36:12120–12137
    [Google Scholar]
53. Daas P.J.H., Gerrits K.A.A., Keltjens J.T., van der Drift C., Vogels G.D. 1993; Involvement of an activation protein in the methanol: 2-mercaptoethanesulfonic acid methyltransferase reaction inMethanosarcina barkeri.. J Bacteriol 175:1278–1283
    [Google Scholar]
54. Daas P.J.H., Hagen W.R., Keltjens J.T., Vogels G.D. 1994; Characterization and determination of the redox properties of the 2[4Fe^lS] ferredoxin fromMethanosarcina barkeri strain MS.. FEBS Lett 356:342–344
    [Google Scholar]
55. Daas P.J.H., Keltjens J.T., Hagen W.R., van der Drift C., Vogels G.D. 1995; The electrochemistry of 5-hydroxybenzimidazolyl- cobamide.. Arch Biochem Biophys 319:244–249
    [Google Scholar]
56. Daas P.J.H., Hagen W.R., Keltjens J.T., van der Drift C., Vogels G.D. 1996a; Activation mechanism of methanol: 5- hydroxybenzimidazolylcobamide methyltransferase fromMethanosarcina barkeri.. J Biol Chem 271:22346–22351
    [Google Scholar]
57. Daas P.J.H., Wassenaar R.W., Willemsen P., Theunissen R.J., Keltjens J.T., van der Drift C., Vogels G.D. 1996b; Purification and properties of an enzyme involved in the ATP- dependent activation of the methanol:2-mercaptoethanesulfonic acid methyltransferase reaction inMethanosarcina barkeri.. J Biol Chem 271:22339–22345
    [Google Scholar]
58. Daniels L. 1993; Biochemistry of methanogenesis.. In The Biochemistry of Archaea (Archaebacteria) pp. 41–112 Kates M., Kushner D.J., Matheson A.T. Edited by New York: Elsevier;
    [Google Scholar]
59. Deppenmeier U. 1995; Different structure and expression of the operons encoding the membrane-bound hydrogenases fromMethanosarcina mazei Gol.. Arch Microbiol 164:370–376
    [Google Scholar]
60. Deppenmeier U., Blaut M., Mahlmann A., Gott&halk G. 1990a; Reduced coenzyme F₄₂₀: heterodisulfide oxidoreductase, a proton-translocating redox system in methanogenic bacteria.. Proc Natl Acad &i USA 87:9449–9453
    [Google Scholar]
61. Deppenmeier U., Blaut M., Mahlmann A., Gott&halk G. 1990b; Membrane-bound F₄₂₀H₂-dependent heterodisulfide reductase in methanogenic bacterium strain Gol andMethanolobus tindarius.. FEBS Lett 261:199–203
    [Google Scholar]
62. Deppenmeier U., Blaut M., Gott&halk G. 1991; H₂:heterodisulfide oxidoreductase, a second energy-conserving system in the methanogenic strain Gol.. Arch Microbiol 155:272–277
    [Google Scholar]
63. Deppenmeier U., Blaut M., Lentes S., Herzberg C., Gott&halk G. 1995; Analysis of thevhoGAC andvhtGAC operons fromMethanosarcina mazei strain Gol, both encoding a membrane- bound hydrogenase and a cytochromeb. . Eur J Biochem 227:261–269
    [Google Scholar]
64. Deppenmeier U., Müller V., Gott&halk G. 1996; Pathways of energy conservation in methanogenic archaea.. Arch Microbiol 165:149–163
    [Google Scholar]
65. Diekert G., Klee B., Thauer R.K. 1980a; Nickel, a component of factor F₄₃₀ fromMethanobacterium thermoautotrophicum.. Arch Microbiol 124:103–106
    [Google Scholar]
66. Diekert G., Jaenchen R., Thauer R.K. 1980b; Biosynthetic evidence for a nickel tetrapyrrole structure of factor F₄₃₀ fromMethanobacterium thermoautotrophicum.. FEBS Lett 119:118–120
    [Google Scholar]
67. Diekert G., Konheiser U., Piechulla K., Thauer R.K. 1981; Nickel requirement and factor F₄₃₀ content of methanogenic bacteria.. J Bacteriol 148:459–464
    [Google Scholar]
68. Eggen R.I.L, Geerling A.C.M., Boshoven A.B.P., de Vos W.M. 1991a; Cloning, sequence analysis, and functional expresion of the acetyl coenzyme A synthetase gene fromMethano- thrix soehngenii inE&herichia coli.. J Bacteriol 173:6383–6389
    [Google Scholar]
69. Eggen R.I.L, Geerling A.C.M., Jetten M.S.M., de Vos W.M. 1991b; Cloning, expression, and sequence analysis of the genes for carbon monoxide dehydrogenase ofMethanothrix soehngenii.. J Biol Chem 266:6883–6887
    [Google Scholar]
70. Eggen R.I.L., van Kranenburg R., Vriesema A.J.M., Geerling A.C.M., Verhagen M.F.J.M., Hagen W.R., de Vos W.M. 1996; . Carbon monoxide dehydrogenase fromMethanosarcina frisia Göl. Characterization of the enzyme and the regulated expression of two operon-like cdh gene clusters.. J Biol Chem 271:14256–14263
    [Google Scholar]
71. Ellefson W.L., Whitman W.B., Wolfe R.S. 1982; Nickel-containing factor F₄₃₀: chromophore of the methylreductase ofMethanobacterium.. Proc Natl Acad &i USA 79:3707–3710. Ellermann
    [Google Scholar]
72. Ellermann J., Hedderich R., Böcher R., Thauer R.K. 1988; The final step in methane formation: investigations with highly purified methyl-CoM reductase (component C) fromMethanobacterium thermoautotrophicum (strain Marburg).. Eur J Biochem 172:669–677
    [Google Scholar]
73. Ellermann J., Rospert S., Thauer R.K., Bokranz M., Klein A., Voges M., Berkessel A. 1989; Methyl-coenzyme-M reductase fromMethanobacterium thermoautotrophicum (strain Marburg) : purity, activity and novel inhibitors.. Eur J Biochem 184:63–68
    [Google Scholar]
74. Elsden S.R. 1981; Hydrogenase 1931–1981. Trends Biochem &i 6:251–253
    [Google Scholar]
75. Elsden S.R., Pirie N.W. 1949; Obituary notice -Marjory Stephenson 1885–1948. J Gen Microbiol 3:328–339
    [Google Scholar]
76. Enßle M., Zirngibl C., Linder D., Thauer R.K. 1991; Coenzyme F₄₂₀ dependent N⁵,N¹⁰-methylenetetrahydromethanopterin dehydrogenase in methanol grownMethanosarcina barkeri.. Arch Microbiol 155:483–490
    [Google Scholar]
77. Ermler U., Merckel M. C., Thauer R. K., Shima S. 1997a; Formylmethanofuran: tetrahydromethanopterin formyltransfer-ase fromMethanopyrus kandleri- new insights into salt-dependence and thermostability.. Structure 5:635–646
    [Google Scholar]
78. Ermler U., Grabarse W., Shima S., Goubeaud M., Thauer R. K. 1997b; Crystal structure of methyl-coenzyme M reductase: the key enzyme of biological methane formation.. &ience 278:1457–1462
    [Google Scholar]
79. E&alante-Semerena J.C., Rinehart K.L. Jr Wolfe R.S. 1984; Tetrahydromethanopterin, a carbon carrier in methanogenesis.. J Biol Chem 259:9447–9455
    [Google Scholar]
80. E&henmoser A. 1988; Vitamin B₁₂: Experimente zur Frage nach dem Ursprung seiner molekularen Struktur.. Angew Chemie 100:5–40
    [Google Scholar]
81. Färber G., Keller W., Kratky C., Pfaltz A., Spinner C., Kobelt A., E&henmoser A. 1991; Coenzyme F430 from methanogenic bacteria: complete assignment of configuration based on an X-ray analysis of 12,13-diepi-F430 pentamethyl ester and on NMR spectro&opy.. Helv Chim Acta 74:697–716
    [Google Scholar]
82. Ferguson D.J. Jr Krzycki J.A. 1997; Reconstitution of trimethylamine-dependent coenzyme M methylation with the trimethylamine corrinoid protein and the isozymes of methyl-transferase II fromMethanosarcina barkeri.. J Bacteriol 179:846–852
    [Google Scholar]
83. Ferguson D.J. Jr Krzycki J.A., Grahame D.A. 1996; Specific roles of methylcobamide: coenzyme M methyltransferase isozymes in metabolism of methanol and methylamines inMethanosarcina barkeri.. J Biol Chem 271:5189–5194
    [Google Scholar]
84. Ferry J.G. 1993a Metbanogenesis: Ecology, Physiology, Biochemistry & Genetics New York & London: Chapman & Hall;
    [Google Scholar]
85. Ferry J.G. 1993b; Fermentation of acetate.. In Metbanogenesis pp. 304–334 Ferry J.G. Edited by New York & London: Chapman & Hall;
    [Google Scholar]
86. Ferry J.G. 1995; CO dehydrogenase.. Annu Rev Microbiol 49:305–333
    [Google Scholar]
87. Ferry J.G. 1997a; Enzymology of the fermentation of acetate to methane byMethanosarcina thermophila.. BioFactors 6:25–35
    [Google Scholar]
88. Ferry J.G. 1997b; Methane: small molecule, big impact.. &ience 278:1413–1414
    [Google Scholar]
89. Fi&her R., Thauer R.K. 1989; Methyltetrahydromethanopterin as an intermediate in methanogenesis from acetate inMethanosarcina barkeri.. Arch Microbiol 151:459–465
    [Google Scholar]
90. Fi&her R., Thauer R.K. 1990; Ferredoxin-dependent methane formation from acetate in cell extracts ofMethanosarcina barkeri(strain MS).. FEBS Lett 269:368–372
    [Google Scholar]
91. Fi&her R., Gärtner P., Yeliseev A., Thauer R.K. 1992; N⁵-Methyltetrahydromethanopterin: coenzyme M methyltransferase in methanogenic archaebacteria is a membrane protein.. Arch Microbiol 158:208–217
    [Google Scholar]
92. Friedmann H.C., Klein A., Thauer R.K. 1991; Biochemistry of coenzyme F430 a nickel porphinoid involved in methanogenesis.. In Biosynthesis of Tetrapyrroles. New Comprehensive Biochemistry pp. 139–154 Jordan P.M. Edited by Amsterdam: Elsevier;
    [Google Scholar]
93. Gärtner P., Ecker A., Fi&her R., Linder D., Fuchs G., Thauer R.K. 1993; Purification and properties of N⁵-methyltetra-hydromethanopterin: coenzyme M methyltransferase fromMeth-anobacterium thermoautotrophicum.. Eur J Biochem 213:537–545
    [Google Scholar]
94. Gärtner P., Weiss D.S., Harms U., Thauer R.K. 1994; N⁵-methyltetrahydromethanopterin: coenzyme M methyltransferase fromMethanobacterium thermoautotrophicum. Catalytic mechanism and sodium ion dependence.. Eur J Biochem 226:465–472
    [Google Scholar]
95. Gorris L.G.M., van der Drift C. 1994; Cofactor contents of methanogenic bacteria reviewed.. BioFactors 4:139–145
    [Google Scholar]
96. Goubeaud M., &hreiner G., Thauer R.K. 1997; Purified methyl-coenzyme M reductase is activated when the enzyme- bound coenzyme F₄₃₀ is reduced to the nickel(I) oxidation state by titanium(III) citrate.. Eur J Biochem 243:110–114
    [Google Scholar]
97. Graf E.G., Thauer R.K. 1981; Hydrogenase fromMethanobacterium thermoautotrophicum, a nickel-containing enzyme.. FEBS Lett 136:165–169
    [Google Scholar]
98. Grahame D.A. 1989; Different isozymes of methylcobalamin:2- mercaptoethanesulfonate methyltransferase predominate in methanol-versus acetate-grownMethanosarcina barkeri.. J Biol Chem 264:12890–12894
    [Google Scholar]
99. Grahame D.A. 1993; Substrate and cofactor reactivity of a carbon monoxide dehydrogenase-corrinoid enzyme complex: stepwise reduction of iron-sulfur and corrinoid centers, the corrinoid Co^2+/1+ redox midpoint potential, and overall synthesis of acetyl-CoA.. Biochemistry 32:10786–10793
    [Google Scholar]
100. Grahame D.A., DeMoll E. 1995; Substrate and accessory protein requirements and thermodynamics of acetyl-CoA synthesis and cleavage inMethanosarcina barkeri.. Biochemistry 34:4617–4624
     [Google Scholar]
101. Grahame D.A., DeMoll E. 1996; Partial reactions catalyzed by protein components of the acetyl-CoA decarbonylase synthase enzyme complex fromMethanosarcina barkeri.. J Biol Chem 271:8352–8358
     [Google Scholar]
102. Grahame D.A., Stadtman T.C. 1993; Redox enzymes of methanogens: physicochemical properties of selected, purified oxidoreductases.. In Methanogenesis pp. 334–359 Ferry J.G. Edited by New York & London: Chapman & Hall;
     [Google Scholar]
103. Grahame D.A., Khangulov S., DeMoll E. 1996; Reactivity of a paramagnetic enzyme-CO adduct in acetyl-CoA synthesis and cleavage.. Biochemistry 35:593–600
     [Google Scholar]
104. Gunsalus R.P., Wolfe R.S. 1978; Chromophoric factors F₃₄₂and F₄₃₀ ofMethanobacterium thermoautotrophicum.. FEMS Microbiol Lett 3:191–193
     [Google Scholar]
105. Gunsalus R.P., Wolfe R.S. 1980; Methyl coenzyme M reductase fromMethanobacterium thermoautotrophicum. Resolution and properties of the components.. J Biol Chem 255:1891–1895
     [Google Scholar]
106. Gunsalus R.P., Romesser J.A., Wolfe R.S. 1978; Preparation of coenzyme M analogues and their activity in the methyl coenzyme M reductase system ofMethanobacterium thermoautotrophicum.. Biochemistry 17:2374–2377
     [Google Scholar]
107. Haase P., Deppenmeier U., Blaut M., Gott&halk G. 1992; Purification and characterization of F₄₂₀H₂-dehydrogenase fromMethanolobus tindarius.. Eur J Biochem 203:527–531
     [Google Scholar]
108. Hammel K.E., Cornwell K.L., Diekert G.B., Thauer R.K. 1984; Evidence for a nickel-containing carbon monoxide dehydrogenase inMethanobrevibacter arboriphilicus.. J Bacteriol 157:975–978
     [Google Scholar]
109. Harms U., Thauer R.K. 1996a; The corrinoid-containing 23-kDa subunit MtrA of the energy-conserving N⁵-methyl-tetrahydromethanopterin: coenzyme M methyltransferase complex fromMethanobacterium thermoautotrophicum. EPR spectro&opic evidence for a histidine residue as a cobalt ligand of the cobamide.. Eur J Biochem 241:149–154
     [Google Scholar]
110. Harms U., Thauer R.K. 1996b; Methylcobalamin: coenzyme M methyltransferase isoenzymes MtaA and MtbA fromMethanosarcina barkeri. Cloning, sequencing and differential tran&ription of the encoding genes, and functional overexpression of themtaA gene inE&herichia coli.. Eur J Biochem 235:653–659
     [Google Scholar]
111. Harms U., Thauer R.K. 1997; Identification of the active site histidine in the corrinoid protein MtrA of the energy-conserving methyltransferase complex fromMethanobacterium thermoautotrophicum.. Eur J Biochem 250:783–788
     [Google Scholar]
112. Harms U., Thauer R.K. 1998; EPR spectro&opic evidence that in the energy-conserving methyltransferase complex from methanogenic Archaea a histidine residue is ligated to the cobamide-cobalt.. In Vitamin B₁₂ and B₁₂-Proteins pp. 157–165 Krautler B., Arigoni D., Golding B.T. Edited by Lectures presented at the 4th European Symposium on Vitamin B₁₂ and B₁₂-Proteins. Weinheim: Wiley-VCH;
     [Google Scholar]
113. Harms U., Weiss D., Gärtner P., Linder D., Thauer R.K. 1995; The energy conserving N⁵-methyltetrahydromethanopterin: coenzyme M methyltransferase complex fromMethanobacterium thermoautotrophicum is composed of eight different subunits.. Eur J Biochem 228:640–648
     [Google Scholar]
114. Hartmann G.C., Klein A.R., Linder M., Thauer R.K. 1996a; Purification, properties and primary structure of H₂-forming N⁵,N¹⁰-methylenetetrahydromethanopterin dehydrogenase fromMethanococcus thermolithotrophicus.. Arch Microbiol 165:187–193
     [Google Scholar]
115. Hartmann G.C., Santamaria E., Fernández V.M., Thauer R.K. 1996b; Studies on the catalytic mechanism of H₂-forming methylenetetrahydromethanopterin dehydrogenase:para-ortho H₂ conversion rates in H₂O and D₂O.. J Biol Inorg Chem 1:446–450
     [Google Scholar]
116. Hartzell P.L., Wolfe R.S. 1986; Requirement of the nickel tetrapyrrole F₄₃₀ forin vitro methanogenesis: reconstitution of methylreductase component C from its dissociated subunits.. Proc Natl Acad &i USA 83:6726–6730
     [Google Scholar]
117. Hartzell P.L., Donnelly M.I., Wolfe R.S. 1987; Incorporation of coenzyme M into component C of methyl-coenzyme M methylreductase duringin vitro methanogenesis.. J Biol Chem 262:5581–5586
     [Google Scholar]
118. Hedderich R., Thauer R.K. 1988; Methanobacterium thermo- autotrophicum contains a soluble enzyme system that specifically catalyzes the reduction of the heterodisulfide of coenzyme M and 7-mercaptoheptanoylthreonine phosphate with H₂.. FEBS Lett 234:223–227
     [Google Scholar]
119. Hedderich R., Berkessel A., Thauer R.K. 1990; Purification and properties of heterodisulfide reductase fromMethanobacterium thermoautotrophicum (strain Marburg).. Eur J Biochem 193:255–261
     [Google Scholar]
120. Hedderich R., Albracht S.P.J., Linder D., Koch J., Thauer R.K. 1992; Isolation and characterization of polyferredoxin fromMethanobacterium thermoautotrophicum. ThemvhB gene product of the methylviologen-reducing hydrogenase operon.. FEBS Lett 298:65–68
     [Google Scholar]
121. Hedderich R., Koch J., Linder D., Thauer R.K. 1994; The heterodisulfide reductase fromMethanobacterium thermoautotrophicum contains sequence motifs characteristic of pyridine- nucleotide-dependent thioredoxin reductases.. Eur J Biochem 225:253–261
     [Google Scholar]
122. Heiden S., Hedderich R., Setzke E., Thauer R.K. 1993; Purification of a cytochromeb containing H₂: heterodisulfide oxidoreductase complex from membranes ofMethanosarcina barkeri.. Eur J Biochem 213:529–535
     [Google Scholar]
123. Heiden S., Hedderich R., Setzke E., Thauer R.K. 1994; Purification of a two-subunit cytochrome-b-containing heterodisulfide reductase from methanol-grownMethanosarcina barkeri.. Eur J Biochem 221:855–861
     [Google Scholar]
124. Heim S., Künkel A., Thauer R.K., Hedderich R. 1998; Thiol: fumarate reductase (Tfr) fromMethanobacterium thermoautotrophicum: identification of the catalytic sites for fumarate reduction and thiol oxidation.. Eur J Biochem 253:292–299
     [Google Scholar]
125. Hochheimer A., &hmitz R.A., Thauer R.K., Hedderich R. 1995; The tungsten formylmethanofuran dehydrogenase fromMethanobacterium thermoautotrophicum contains sequence motifs characteristic for enzymes containing molybdopterin dinucleotide.. Eur J Biochem 234:910–920
     [Google Scholar]
126. Hochheimer A., Linder D., Thauer R.K., Hedderich R. 1996; The molybdenum formylmethanofuran dehydrogenase operon and the tungsten formylmethanofuran dehydrogenase operon fromMethanobacterium thermoautotrophicum: structures and tran&riptional regulation.. Eur J Biochem 242:156–162
     [Google Scholar]
127. Holliger C., Pierik A.J., Reijerse E.J., Hagen W.R. 1993; A spectroelectrochemical study of factor F₄₃₀ nickel(II/I) from methanogenic bacteria in aqueous solution.. J Am Chem Soc 115:5651–5656
     [Google Scholar]
128. Holm L. 1997; An evolutionary treasure: unification of a broad set of amidohydrolases related to urease.. Proteins Struct Funct Genet 28:72–82
     [Google Scholar]
129. Howell D.M., Harich K., Xu H., White R.H. 1998; The ɑ-keto acid chain elongation reactions involved in the biosynthesis of 7-mercaptoheptanoylthreonine-phosphate in methanogenic archaea.. Biochemistry (in press)
     [Google Scholar]
130. Hungerer C., Weiss D.S., Thauer R.K., Jahn D. 1996; ThehemA gene encoding glutamyl-tRNA reductase from the archaeonMethanobacterium thermoautotrophicum strain Marburg.. Bio- org Med Chem 4:1089–1095
     [Google Scholar]
131. Inatomi K.I. 1996; ATP-dependent H⁺-pump activity in inverted vesicles ofMethanosarcina mazei Gol and characterization of membrane ATPase.. J Bacteriol 178:2424–2426
     [Google Scholar]
132. Ito N., Phillips S.E.V., Stevens C., Ogel Z.B., McPherson M.J., Keen J.N., Yadav K.D.S., Knowles P.F. 1991; Novel thioether bond revealed by a 1·7 Å crystal structure of galactose oxidase.. Nature 350:87–90
     [Google Scholar]
133. Jäger E.-G., Rudolph M. 1997; Cyclic voltammetric and impedance spectrometric investigations on addition/elimination reactions of Lewis bases accompanying the electrode reactions of a nickel chelate complex with a structural resemblance to the coenzyme F430.. J Electroanal Chem 434:1–18
     [Google Scholar]
134. Jaun B. 1990; Coenzyme F430 from methanogenic bacteria: oxidation of F430 pentamethyl ester to the Ni(III) form.. Helv Chim Acta 73:2209–2217
     [Google Scholar]
135. Jaun B. 1993; Methane formation by methanogenic bacteria: redox chemistry of coenzyme F430.. In Metal Ions in Biological Systems 29 Properties of Metal Alkyl Derivatives pp. 287–337 Sigel H., Sigel A. Edited by New York: Marcel Dekker;
     [Google Scholar]
136. Jaun B., Pfaltz A. 1986; Coenzyme F430 from methanogenic bacteria: reversible one-electron reduction of F430 pentamethyl ester to the nickel(I) form.. J Chem Soc Chem Commun1327–1329
     [Google Scholar]
137. Jaun B., Pfaltz A. 1988; Coenzyme F430 from methanogenic bacteria: methane formation by reductive carbon-sulphur bond cleavage of methyl sulphonium ions catalysed by F430 penta-methyl ester.. J Chem Soc Chem Commun293–294
     [Google Scholar]
138. Kaesler B., &hönheit P. 1989a; The role of sodium ions in methanogenesis. Formaldehyde oxidation to C0₂ and 2H₂ in methanogenic bacteria is coupled with primary electrogenic Na⁺translocation at a stoichiometry of 2–3 Na⁺/C0₂.. Eur J Biochem 184:223–232
     [Google Scholar]
139. Kaesler B., &hönheit P. 1989b; The sodium cycle in methanogenesis. CO₂ reduction to the formaldehyde level in methanogenic bacteria is driven by a primary electrochemical potential of Na⁺ generated by formaldehyde reduction to CH₄.. Eur J Biochem 186:309–316
     [Google Scholar]
140. Kamp A.F., la Rivière J.W.M., Verhoeven W. 1959 Albert Jan Kluyver, His Life and Work Amsterdam: North-Holland Publishing;
     [Google Scholar]
141. Kandler O., König H. 1998; Cell wall polymers in Archaea (Archaebacteria).. Cell Mol Life &i 54:305–308
     [Google Scholar]
142. Keltjens J.T., Vogels G.D. 1993; Conversion of methanol and methylamines to methane and carbon dioxide.. In Methano-genesis pp. 253–303 Ferry J.G. Edited by New York & London: Chapman & Hall;
     [Google Scholar]
143. Kemner J. M., Zeikus J. G. 1994a; Purification and charac-terization of membrane-bound hydrogenase fromMethano-sarcina barkeri MS.. Arch Microbiol 16147–54
     [Google Scholar]
144. Kemner J. M., Zeikus J. G. 1994b; Regulation and function of ferredoxin-linked versus cytochromeb-linked hydrogenase in electron transfer and energy metabolism ofMethanosarcina barkeri MS.. Arch Microbiol 16226–32
     [Google Scholar]
145. Klein A.R., Thauer R.K. 1995; Re-face specificity at C14a of methylenetetrahydromethanopterin and Si-face specificity at C5 of coenzyme F₄₂₀ for coenzyme F₄₂₀-dependent methylene- tetrahydromethanopterin dehydrogenase from methanogenic Ar- chaea.. Eur J Biocbem 227:169–174
     [Google Scholar]
146. Klein A.R., Thauer R.K. 1997; Overexpression of the coenzyme F₄₂₀-dependent N⁵,N¹⁰-methylenetetrahydromethan- opterin dehydrogenase gene from the hyperthermophilicMeth- anopyrus kandleri. . Eur J Biocbem 245:386–391
     [Google Scholar]
147. Klein A.R., Breitung J., Linder D., Stetter K. O., Thauer R. K. 1993a; N⁵,N¹⁰-Methenyltetrahydromethanopterin cyclo-hydrolase from the extremely thermophilic sulfate reducingArcbaeoglobus fulgidus: comparison of its properties with those of the cyclohydrolase from the extremely thermophilicMetb- anopyrus kandleri. . Arch Microbiol 159:213–219
     [Google Scholar]
148. Klein A.R., Koch J., Stetter K.O., Thauer R.K. 1993b; Two N⁵,N¹⁰-methylenetetrahydromethanopterin dehydrogenases in the extreme thermophileMethanopyrus kandleri: charac-terization of the coenzyme F₄₂₀-dependent enzyme.. Arch Micro-biol 160:186–192
     [Google Scholar]
149. Klein A.R., Fernandez V.M., Thauer R.K. 1995a; H₂-forming N⁵,N¹⁰-methylenetetrahydromethanopterin dehydrogenase: me-chanism of H₂ formation analyzed using hydrogen isotopes.. FEBS Lett 368203–206
     [Google Scholar]
150. Klein A.R., Hartmann G.C., Thauer R.K. 1995b; Hydrogen isotope effects in the reactions catalyzed by H₂-forming N⁵,N¹⁰- methylenetetrahydromethanopterin dehydrogenase from meth-anogenic Archaea.. Eur J Biocbem 233372–376
     [Google Scholar]
151. Klein A.R., Berk H., Purwantini E., Daniels L., Thauer R.K. 1996; Si-face stereospecificity at C5 of coenzyme F₄₂₀ for F₄₂₀- dependent glucose-6-phosphate dehydrogenase fromMycobac-terium smegmatis and F₄₂₀-dependent alcohol dehydrogenase fromMethanoculleus tbermophilicus. . Eur J Biocbem 239:93–97
     [Google Scholar]
152. Klenk H.-P., Clayton R.A., Tomb J.-F. 48 other authors 1997; The complete genome sequence of the hyperthermophilic, sul-phate-reducing archaeonArcbaeoglobus fulgidus. . Nature 390:364–370
     [Google Scholar]
153. Knight M., Wolfe R.S., Elsden S.R. 1966; The synthesis of amino acids byMethanobacterium omelianskii. . Biocbem J 99:76–86
     [Google Scholar]
154. Kräutler B., Arigoni D., Golding B.T. 1998 Vitamin B₁₂ and B₁₂-Proteins Weinheim: Wiley-VCH;
     [Google Scholar]
155. Kuhner C.H., Lindenbach B.D., Wolfe R.S. 1993; Com-ponent A2 of methylcoenzyme M reductase system fromMeth-anobacterium thermoautotrophicum △H: nucleotide sequence and functional expression byE&herichia coli. . J Bacteriol 175:3195–3203
     [Google Scholar]
156. Kumazawa Y., Fujiwara T., Fukumori Y., Koga Y., Yamanaka T. 1994; Cytochromebe purified from the methanogenMetb- anosarcina barkeri. . Curr Microbiol 29:53–56
     [Google Scholar]
157. Künkel A., Vaupel M., Heim S., Thauer R.K., Hedderich R. 1997; Heterodisulfide reductase from methanol-grown cells ofMethanosarcina barkeri is not a flavoenzyme.. Eur J Biocbem 244:226–234
     [Google Scholar]
158. Künkel A., Vorholt J.A., Thauer R.K., Hedderich R. 1998; AnE. coli hydrogenase 3 type hydrogenase in methanogenic archaea.. Eur J Biocbem 252:A67–A76
     [Google Scholar]
159. Kunow J., &hwörer B., Setzke E., Thauer R.K. 1993; Si-face stereospecificity at C5 of coenzyme F₄₂₀ for F₄₂₀-dependent N⁵,N¹⁰-methylenetetrahydromethanopterin dehydrogenase, F₄₂₀- dependent N⁵,N¹⁰-methylenetetrahydromethanopterin reductase and F₄₂₀H₂:dimethylnaphthoquinone oxidoreductase.. Eur J Bio-cbem 214:641–646
     [Google Scholar]
160. Kunow J., Linder D., Stetter K.O., Thauer R.K. 1994; F₄2oH₂:q^uin^one oxidoreductase fromArcbaeoglobus fulgidus:characterization of a membrane-bound multisubunit complex containing FAD and iron-sulfur clusters.. Eur J Biocbem 223:503–511
     [Google Scholar]
161. Kunow J., Linder D., Thauer R.K. 1995; Pyruvate :ferredoxin oxidoreductase from the sulfate-reducingArcbaeoglobus ful-gidus : molecular composition, catalytic properties and sequence alignments.. Arch Microbiol 163:21–28
     [Google Scholar]
162. Kunow J., Shima S., Vorholt J.A., Thauer R.K. 1996; Primary structure and properties of the formyltransferase from the mesophilicMethanosarcina barkeri: comparison with the en-zymes from thermophilic and hyperthermophilic methanogens.. Arch Microbiol 165:97–105
     [Google Scholar]
163. Latimer M.T., Ferry J.G. 1993; Cloning, sequence analysis, and hyperexpression of the genes encoding phosphotransacetylase and acetate kinase fromMethanosarcina tbermophila. . J Bacteriol 175:6822–6829
     [Google Scholar]
164. LeClerc G.M., Grahame D.A. 1996; Methylcobamide: coenzyme M methyltransferase isozymes fromMethanosarcina barkeri: physicochemical characterization, cloning, sequence analysis and heterologous gene expression.. J Biol Cbem 271:18725–18731
     [Google Scholar]
165. Lehmacher A. 1994; Cloning, sequencing and tran&ript analysis of the gene encoding formylmethanofuran: tetrahydromethano-pterin formyltransferase from the hyperthermophilicMeth- anotbermus fervidus. . Mol Gen Genet 242:73–80
     [Google Scholar]
166. Lehmacher A., Klenk H.P. 1994; Characterization and phylogeny of racrll, a gene cluster encoding an isoenzyme of methyl coenzyme M reductase from hyperthermophilicMeth- anotbermus fervidus. . Mol Gen Genet 243:198–206
     [Google Scholar]
167. Lenz R., Giese B. 1997; Studies on the mechanism of ribonucleotide reductases.. J Am Cbem Soc 119:2784–2794
     [Google Scholar]
168. Lexa D., Saveant J.-M. 1983; The electrochemistry of vitamin B₁₂.. Acc Cbem Res 16:235–243
     [Google Scholar]
169. Lienard T., Gott&halk G. 1998; Cloning, sequencing and expression of the genes encoding the sodium translocating N⁵- methyltetrahydromethanopterin: coenzyme M methyltransferase of the methylotrophic archaeonMethanosarcina mazei Gol.. FEBS Lett 425:204–208
     [Google Scholar]
170. Lienard T., Becher B., Mar&hall M., Bowien S., Gott&halk G. 1996; Sodium ion translocation by N⁵-methyltetrahydro- methanopterin: coenzyme M methyltransferase fromMethano-sarcina mazei Gol reconstituted in ether lipid liposomes.. Eur J Biocbem 239:857–864
     [Google Scholar]
171. Lin S.-K., Jaun B. 1991; Coenzyme F430 from methanogenic bacteria: detection of a paramagnetic methylnickel(II) derivative of the pentamethyl ester by²H-NMR spectro&opy.. Helv Cbim Acta 74:1725–1738
     [Google Scholar]
172. Lin S.-K., Jaun B. 1992; Coenzyme F430 from methanogenic bacteria: mechanistic studies on the reductive cleavage of sulfonium ions catalyzed by F430 pentamethyl ester.. Helv Cbem Acta 75:1478–1490
     [Google Scholar]
173. Lovley D.R., White R.H., Ferry J.G. 1984; Identification of methyl coenzyme M as an intermediate in methanogenesis from acetate inMethanosarcina spp.. J Bacteriol 160:521–525
     [Google Scholar]
174. Lu W.-P., Jablonski P.E., Ra&he M., Ferry J.G., Ragsdale S.W. 1994; Characterization of the metal centers of the Ni/Fe-S component of the carbon-monoxide dehydrogenase enzyme complex fromMethanosarcina tbermophila. . J Biol Cbem 269:9736–9742
     [Google Scholar]
175. Lu W.-P., Becher B., Gott&halk G., Ragsdale S.W. 1995; Electron paramagnetic resonance spectro&opic and electro-chemical characterization of the partially purified N⁵-methyl- tetrahydromethanopterin: coenzyme M methyltransferase fromMethanosarcina mazei Gol.. J Bacteriol 177:2245–2250
     [Google Scholar]
176. Ma K., Thauer R.K. 1990; N⁵,N¹⁰-Methylenetetrahydro- methanopterin reductase fromMethanosarcina barkeri. . FEMS Microbiol Lett 70:119–124
     [Google Scholar]
177. Mancia F., Keep N.H., Nakagawa A., Leadlay P.F., McSweeney S., Rasmussen B., Bösecke P., Diat O., Evans P.R. 1996; How coenzyme B₁₂ radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 Å resolution.. Structure 4:339–350
     [Google Scholar]
178. Mansel V., Klar G. 1992; Organometalloidal compounds with o-phenylene substituents. Part 25. Crystal and molecular struc-tures of 2,3,7,8-tetrahydroxythianthrene.. J Chem Res (Suppl.)158–159
     [Google Scholar]
179. Maroney M.J., Davidson G., Allan C.B., Figlar J. 1998; The structure and function of nickel sites in metalloproteins.. Struct Bonding 92:1–66
     [Google Scholar]
180. Martin W., Müller M. 1998; The hydrogen hypothesis for the first eukaryote.. Nature 392:37–41
     [Google Scholar]
181. Mason J. 1992; The admission of the first women to the Royal Society of London.. Notes Rec R Soc Lond 46:279–300
     [Google Scholar]
182. Mason J. 1996; Marjory Stephenson 1885-1948.. In Cambridge Women: Twelve Portraits pp. 113–135 Cambridge: Cambridge University Press;
     [Google Scholar]
183. Maupin-Furlow J., Ferry J.G. 1996a; Analysis of the CO dehydrogenase/acetyl-coenzyme A synthase operon ofMethano-sarcina tbermophila. . J Bacteriol 178:6849–6856
     [Google Scholar]
184. Maupin-Furlow J., Ferry J.G. 1996b; Characterization of thecdhD andcdhE genes encoding subunits of the corrinoid/ iron-sulfur enzyme of the CO dehydrogenase complex fromMethanosarcina tbermophila. . J Bacteriol 178:340–346
     [Google Scholar]
185. Metcalf W.W., Zhang J.K., Apolinario E., Sowers K.R., Wolfe R.S. 1997; A genetic system for archaea of the genusMethanosarcina-. liposome-mediated transformation and con-struction of shuttle vectors.. Proc Natl Acad &i USA 94:2626–2631
     [Google Scholar]
186. Morgan R.M., Pihl T.D., Nölling J., Reeve J.N. 1997; Hydrogen regulation of growth, growth yields, and methane gene tran&ription inMethanobacterium thermoautotrophicum AH.. J Bacteriol 179:889–898
     [Google Scholar]
187. Mukhopadhyay B., Purwantini E., Pihl T.D., Reeve J.N., Daniels L. 1995; Cloning, sequencing, and tran&riptional analysis of the coenzyme F₄₂₀-dependent methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase gene fromMethano-bacterium thermoautotrophicum strain Marburg and functional expression inE&herichia coli. . J Biol Chem 270:2827–2832
     [Google Scholar]
188. Müller V., Gott&halk G. 1994; The sodium ion cycle in acetogenic and methanogenic bacteria: generation and utilization of a primary electrochemical sodium ion gradient.. In Acetogen- esis pp. 127–156 Drake H.L. Edited by New York & London: Chapman & Hall;
     [Google Scholar]
189. Noll K.M., Wolfe R.S. 1986; Component C of the methyl- coenzyme M methylreductase system contains bound 7-mercap- toheptanoyl phosphate (HS-HTP).. Biochem Biophys Res Commun 139:889–895
     [Google Scholar]
190. Noll K.M., Rinehart K.L. JR Tanner R.S., Wolfe R.S. 1986; Structure of component B (7-mercaptoheptanoylthreonine phos-phate) of the methyl-coenzyme M methylreductase system ofMethanobacterium thermoautotrophicum. . Proc Natl Acad &i USA 83:4238–1242
     [Google Scholar]
191. Nölling J., Reeve J.N. 1997; Growth- and substrate-dependent tran&ription of the formate dehydrogenase (fdhCAB) operon inMethanobacterium thermoformicicum Z-245.. J Bacteriol 179:899–908
     [Google Scholar]
192. Nölling J., Pihl T.D., Reeve J.N. 1995a; Cloning, sequencing, and growth phase-dependent tran&ription of the coenzyme F₄₂₀- dependent N⁵,N¹⁰-methylenetetrahydromethanopterin reduc-tase-encoding genes fromMethanobacterium thermoautotroph-icum △H andMethanopyrus kandleri. . J Bacteriol 177:7238–7244
     [Google Scholar]
193. Nölling J., Pihl T.D., Vriesema A., Reeve J.N. 1995b; Organization and growth phase-dependent tran&ription of methane genes in two regions of theMethanobacterium thermo-autotrophicum genome.. J Bacteriol 177:2460–2468
     [Google Scholar]
194. Nölling J., Ishii M., Koch J., Pihl T.D., Reeve J.N., Thauer R.K., Hedderich R. 1995c; Characterization of a 45-kDa flavoprotein and evidence for a rubredoxin, two proteins that could participate in electron transport from H₂ to CO₂ in methanogenesis inMethanobacterium thermoautotrophicum. . Eur J Biochem 231:628–638
     [Google Scholar]
195. Nölling J., Elfner A., Palmer J.R., Steigerwald V.J., Pihl T.D., Lake J.A., Reeve J.N. 1996; Phylogeny ofMethanopyrus kandleri based on methyl-coenzyme M reductase operons.. Int J Syst Bacteriol 46:1170–1173
     [Google Scholar]
196. Olson K.D., Chmurkowska-Cichowlas L., McMahon C.W., Wolfe R.S. 1992; Structural modifications and kinetic studies of the substrates involved in the final step of methane formation inMethanobacterium thermoautotrophicum. . J Bacteriol 174:1007–1012
     [Google Scholar]
197. Pandiyan T., Bernés S., de Bazúa C.D. 1997; Structure, spectra and redox studies of nickel(II) bis(benzimidazolyle-2- ylmethyl)amines with coenzyme M reductase.. Polyhedron 16:2819–2826
     [Google Scholar]
198. Paul L., Krzycki J.A. 1996; Sequence and tran&ript analysis of a novelMethanosarcina barkeri methyltransferase II homolog and its associated corrinoid protein homologous to methionine synthase.. J Bacteriol 178:6599–6607
     [Google Scholar]
199. Peer C.W., Painter M.H., Ra&he M.E., Ferry J.G. 1994; Characterization of a CO: heterodisulfide oxidoreductase system from acetate-grownMethanosarcina tbermophila. . J Bacteriol 176:6974–6979
     [Google Scholar]
200. Peinemann S., Hedderich R., Blaut M., Thauer R.K., Gotts-chalk G. 1990; ATP synthesis coupled to electron transfer from H₂ to the heterodisulfide of 2-mercaptoethanesulfonate and 7- mercaptoheptanoylthreonine phosphate in vesicle preparations of the methanogenic bacterium strain Göl.. FEBS Lett 263:57–60
     [Google Scholar]
201. Pennings J.L.A., de Wijs J.L.J., Keltjens J.T., van der Drift C. 1997; Medium-reductant directed expression of methyl coenzyme M reductase isoenzymes inMethanobacterium thermoautotrophicum (strain AH).. FEBS Lett 410:235–237
     [Google Scholar]
202. Pfaltz A., Jaun B., Fässler A., E&henmoser A., Jaenchen R., Gilles H.H., Diekert G., Thauer R.K. 1982; Zur Kenntnis des Faktors F430 aus methanogenen Bakterien: Struktur des por- phinoiden Ligandsystems.. Helv Chim Acta 65:828–865
     [Google Scholar]
203. Picot D., Loll P.J., Garavito R.M. 1994; The X-ray crystal structure of the membrane protein prostaglandin H₂ synthase-1.. Nature 367:243–249
     [Google Scholar]
204. Pihl T.D., Sharma S., Reeve J.N. 1994; Growth phase- dependent tran&ription of the genes that encode the two methyl coenzyme M reductase isoenzymes and N⁵-methyltetrahydro- methanopterin: coenzyme M methyltransferase inMethano-bacterium thermoautotrophicum ΔH.. J Bacteriol 176:6384–6391
     [Google Scholar]
205. Postgate J. 1995 Society for General Microbiology: Fifty Years On Special Publication of the Society for General Microbiology;
     [Google Scholar]
206. Reeve J.N., Beckler G.S., Cram D.S. 7 other authors 1989; A hydrogenase-linked gene inMetbanobacterium tbermo- autotropbicum strain ΔH encodes a polyferredoxin.. Proc Natl Acad Set USA 86:3031–3035
     [Google Scholar]
207. Reeve J.N., Nölling J., Morgan R.M., Smith D.R. 1997; Methanogenesis: genes, genomes, and who’s on first.. J Bacteriol 179:5975–5986
     [Google Scholar]
208. Roach P.L., Clifton I.J., Hensgens C.M.H., Shibata N., &hofield C.J., Hajdu J., Baldwin J.E. 1997; Structure of isopenicillin N synthase complexed with substrate and mechanism of penicillin formation.. Nature 387:827–830
     [Google Scholar]
209. Robertson M. 1949; Marjory Stephenson (1885-1948).. Obituary Notices of Fellows of the Royal Society 6:563–575
     [Google Scholar]
210. Rospert S. 1991 ESR-Eigen&haften der Metbyl-CoM-Reduk- tase aus Metbanobacterium tbermoautotropbicum und ibre Korrelation zur Enzymtätigkeit Dissertation, Philipps-Univer- sitat Marburg;
     [Google Scholar]
211. Rospert S., Linder D., Ellermann J., Thauer R.K. 1990; Two genetically distinct methyl-coenzyme M reductases inMeth- anobacterium tbermoautotropbicum strain Marburg and AH.. Eur J Biocbem 194:871–877
     [Google Scholar]
212. Rospert S., Böcher R., Albracht S.P.J., Thauer R.K. 1991; Methyl-coenzyme M reductase preparations with high specific activity from H₂-preincubated cells ofMetbanobacterium ther- moautotrophicum. . FEBS Lett 291:371–375
     [Google Scholar]
213. Rospert S., Voges M., Berkessel A., Albracht S.P.J., Thauer R.K. 1992; Substrate-analogue-induced changes in the nickel EPR spectrum of active methyl-coenzyme-M reductase fromMetbanobacterium tbermoautotropbicum. . Eur J Biocbem 210:101–107
     [Google Scholar]
214. Ruppert C., Wimmers S., Lemker T., Muller V. 1998; The A₁A₀ ATPase fromMethanosarcina mazei: cloning of the5´ end of theaha operon encoding the membrane domain and expression of the proteolipid in a membrane-bound form inE&herichia coli. . J Bacteriol 180:3448–3452
     [Google Scholar]
215. Sauer F.D. 1991; Inhibition of methylcoenzyme M methyl- reductase by a uridine 5´-diphospho-N-acetylglucosamine derivative.. Biocbem Biophys Res Commun 174:619–624
     [Google Scholar]
216. Sauer F.D., Blackwell B.A., Kramer J.K.G., Marsden B.J. 1990; Structure of a novel cofactor containingN-(7-mercapto- heptanoyl)-O-3-phosphothreonine.. Biochemistry 29:7593–7600
     [Google Scholar]
217. Sauer K., Thauer R.K. 1997; Methanol: coenzyme M methyl- transferase fromMethanosarcina barkeri. Zinc dependence and thermodynamics of the methanol: cob(I)alamin methyltransferase reaction.. Eur J Biocbem 249:280–285
     [Google Scholar]
218. Sauer K., Thauer R.K. 1998; Methanol: coenzyme M methyltransferase fromMethanosarcina barkeri: identification of the active-site histidine in the corrinoid-harboring subunit MtaC by site-directed mutagenesis.. Eur J Biocbem 253:698–705
     [Google Scholar]
219. Sauer K., Harms U., Thauer R.K. 1997; Methanol: coenzyme M methyltransferase fromMethanosarcina barkeri: purification, properties and encoding genes of the corrinoid protein MT1.. Eur J Biocbem 243:670–677
     [Google Scholar]
220. Sauter M., Böhm R., Böck A. 1992; Mutational analysis of the operon(bye) determining hydrogenase 3 formation inE&herichia coli. . Mol Microbiol 6:1523–1532
     [Google Scholar]
221. &hauder R., Kröger A. 1993; Bacterial sulphur respiration.. Arch Microbiol 159:491–497
     [Google Scholar]
222. &hleucher J., Griesinger C., &hwörer B., Thauer R.K. 1994; H₂-forming N⁵,N¹⁰-methylenetetrahydromethanopterin dehydrogenase fromMetbanobacterium tbermoautotropbicum catalyzes a stereoselective hydride transfer as determined by two-dimensional NMR spectro&opy.. Biochemistry 33:3986–3993
     [Google Scholar]
223. &hleucher J., &hwörer B., Thauer R.K., Griesinger C. 1995; Elucidation of the stereochemical course of chemical reactions by magnetic labeling.. J Am Cbem Soc 117:2941–2942
     [Google Scholar]
224. &hmid C.L., Kempf C., Taubert A., Neuburger M., Zehnder M., Kaden T.A., Bujno K., Bilewicz R. 1996; Metal complexes with macrocyclic ligands. Part XLII. Tetraazamacrocyclic nickel(III) complexes with a methylthio or a methoxy pendant chain as model for cofactor F430.. Helv Chim Acta 79:1011–1020
     [Google Scholar]
225. &hmid C.L., Neuburger M., Zehnder M., Kaden T.A., Bujno K., Bilewicz R. 1997; Metal complexes with macrocyclic ligands. Part XLIII. Tetraazamacrocyclic nickel(II) and copper(II) complexes with aliphatic methylthio- and methoxy-substituted pendant chains.. Fielv Chim Acta 80:241–252
     [Google Scholar]
226. &hmitz R.A., Bertram P.A., Thauer R.K. 1994; Tungstate does not support synthesis of active formylmethanofuran dehydrogenase inMethanosarcina barkeri. . Arch Microbiol 161:528–530
     [Google Scholar]
227. &hönheit P., Beimborn D.B. 1985; Presence of a Na⁺/H⁺antiporter inMetbanobacterium tbermoautotropbicum and its role in Na⁺ dependent methanogenesis.. Arch Microbiol 142:354–361
     [Google Scholar]
228. &hönheit P., Moll J., Thauer R.K. 1979; Nickel, cobalt, and molybdenum requirement for growth ofMetbanobacterium tbermoautotropbicum. . Arch Microbiol 123:105–107
     [Google Scholar]
229. &hönheit P., Moll J., Thauer R.K. 1980; Growth parameters (K₂, μ_max, Y_s) ofMetbanobacterium tbermoautotropbicum. . Arch Microbiol 121:59–65
     [Google Scholar]
230. &hwörer P., Breitung J., Klein A. R., Stetter K. O., Thauer R.K. 1993a; Formylmethanofuran :tetrahydromethanopterin formyltransferase and N⁵,N¹⁰-methylenetetrahydromethanop- terin dehydrogenase from the sulfate-reducingArchaeoglobus fulgidus: similarities with the enzymes from methanogenic Archaea.. Arch Microbiol 159:225–232
     [Google Scholar]
231. &hwörer P., Fernandez V. M., Zirngibl C., Thauer R.K. 1993b; H₂-forming N⁵,N¹⁰-methylenetetrahydromethanopterin dehydrogenase fromMetbanobacterium tbermoautotropbicum.Studies of the catalytic mechanism of the H₂ formation with hydrogen isotopes.. Eur J Biocbem 212:255–261
     [Google Scholar]
232. Setzke E., Hedderich R., Heiden S., Thauer R.K. 1994; H₂: heterodisulfide oxidoreductase complex fromMethano- bacterium tbermoautotropbicum: composition and properties.. Eur J Biocbem 220:139–148
     [Google Scholar]
233. Shapiro S., Wolfe R.S. 1980; Methyl-coenzyme M, an intermediate in methanogenic dissimilation of C_x compounds byMethanosarcina barkeri. . J Bacteriol 141:728–734
     [Google Scholar]
234. Sherf B.A., Reeve J.N. 1990; Identification of themcrD gene product and its association with component C of methyl coenzyme M reductase inMethanococcus vannielii. . J Bacterio 172:1828–1833
     [Google Scholar]
235. Shima S., Weiss D.S., Thauer R.K. 1995; Formylmethanofuran : tetrahydromethanopterin formyltransferase (Ftr) from the hyperthermophilicMetbanopyrus kandleri: cloning, sequencing and functional expression of theftr gene and one step purification of the enzyme overproduced inE&herichia coli. . Eur J Biocbem 230:906–913
     [Google Scholar]
236. Shima S., Thauer R.K., Michel H., Ermler U. 1996; Crystallization and preliminary X-ray diffraction studies of a forämylmethanofuran : tetrahydromethanopterin formyltransferase fromMetbanopyrus kandleri. . Proteins Struct Fund Genet 26:118–120
     [Google Scholar]
237. Shima S., Goubeaud M., Vinzenz D., Thauer R.K., Ermler U. 1997; Crystallization and preliminary X-ray diffraction studies of methyl-coenzyme M reductase fromMethanobacterium ther- moautotrophicum. . J Biochetn 121:829–830
     [Google Scholar]
238. Singh-Wissmann K., Ferry J.G. 1995; Tran&riptional regulation of the phosphotransacetylase-encoding and acetate kinaseäencoding genes(pta andack) fromMethanosarcina tbermopbila. . J Bacteriol 177:1699–1702
     [Google Scholar]
239. Smigan P., Majernik A., Greksak M. 1994; Na⁺-driven ATP synthesis inMethanobacterium thermoautotrophicum and its differentiation from H⁺-driven ATP synthesis by rhodamine 6G.. FEBS Lett 347:190–194
     [Google Scholar]
240. Smith D.R., Doucette-Stamm L.A., Deloughery C. 34 other authors 1997; Complete genome sequence ofMethano-bacterium thermoautotrophicum AH: functional analysis and comparative genomics.. J Bacteriol 179:7135–7155
     [Google Scholar]
241. Sorgenfrei O., Müller S., Pfeiffer M., Sniezko I., Klein A. 1997a; The [NiFe] hydrogenases ofMethanococcus voltae:genes, enzymes and regulation.. Arch Microbiol 167:189–195
     [Google Scholar]
242. Sorgenfrei O., Duin E. C., Klein A., Albracht S. P. J. 1997b; Changes in the electronic structure around Ni in oxidized and reduced selenium-containing hydrogenases fromMethanococcus voltae. . Eur J Biochem 247:681–687
     [Google Scholar]
243. Sowers K.R., Thai T.T., Gunsalus R.P. 1993; Tran&riptional regulation of the carbon monoxide dehydrogenase gene (cdhA) inMethanosarcina thermophila. . J Biol Chem 268:23172–23178
     [Google Scholar]
244. Sparling R., Blaut M., Gott&halk G. 1993; Bioenergetic studies ofMethanosphaera stadtmanae, an obligate H₂-methanol utilising methanogen.. Can J Microbiol 39:742–748
     [Google Scholar]
245. Springer E., Sachs M.S., Woese C.R., Boone D.R. 1995; Partial gene sequences for the A subunit on methyl-coenzyme M reductase(mcr\) as a phylogenetic tool for the familyMethano- sarcinaceae. . Int J Syst Bacteriol 45:554–559
     [Google Scholar]
246. Sprott G.D., Beveridge T.J. 1993; Micro&opy.. In Methano- genesis pp. 81–127 Edited by Ferry J. G. New York & London: Chapman & Hall;
     [Google Scholar]
247. Stadtman T.C. 1967; Methane fermentation.. Annu Rev Microbiol 21:121–142
     [Google Scholar]
248. Stephenson M. 1932; The chemistry of the bacteria.. Annu Rev Biochem 1:637–654
     [Google Scholar]
249. Stephenson M. 1933; The chemistry of bacteria.. Annu Rev Biochem 2:485–502
     [Google Scholar]
250. Stephenson M. 1934; The chemistry of bacteria.. Annu Rev Biochem 3:519–534
     [Google Scholar]
251. Stephenson M. 1935; The chemistry of bacteria.. Annu Rev Biochem 4:593–614
     [Google Scholar]
252. Stephenson M. 1948; Obituary Notice.Frederick Gowland Hopkins, 1861-1947. Biochem J 42:161–169
     [Google Scholar]
253. Stephenson M. 1949 Bacterial Metabolism, 3rd edn.. London: Longmans, Green and Co;
     [Google Scholar]
254. Stephenson M., Stickland L. H. 1931a; XXVII. Hydrogenase: a bacterial enzyme activating molecular hydrogen. I. The properties of the enzyme.. Biochem J 25:205–214
     [Google Scholar]
255. Stephenson M., Stickland L. H. 1931b; XXVIII. Hydrogenase. II. The reduction of sulphate to sulphide by molecular hydrogen.. Biochem J 25:215–220
     [Google Scholar]
256. Stephenson M., Stickland L.H. 1932; LXXXVIII. Hydro- genlyases. Bacterial enzymes liberating molecular hydrogen.. Biochem J 26:712–725
     [Google Scholar]
257. Stephenson M., Stickland L.H. 1933a; CCVII. Hydrogenase. III. The bacterial formation of methane by the reduction of one- carbon compounds by molecular hydrogen.. Biochem J 27:1517–1527
     [Google Scholar]
258. Stephenson M., Stickland L.H. 1933b; CCVIII. Hydro- genlyases. III. Further experiments on the formation of formic hydrogenlyase byBad. coli. . Biochem J 27:1528–1532
     [Google Scholar]
259. Stickland L.H. 1929; CXXXI. The bacterial decomposition of formic acid.. Biochem J 23:1187–1198
     [Google Scholar]
260. Stinson S. 1995; Hydrogenase enzyme shows unique mechanism.. Chem Eng News October 30:7
     [Google Scholar]
261. Stolzenberg A.M., Zhang Z. 1997; F430 model chemistry. An investigation of nickel complexes as catalysts for the reduction of alkyl halides and methyl coenzyme-M sodium borohydride.. Inorg Chem 36:593–600
     [Google Scholar]
262. Stroup D., Reeve J. N. 1993a; Identification of themcrC gene product inMethanococcus vannielii.. FEMS Microbiol Lett 111:129–134
     [Google Scholar]
263. Stroup D., Reeve J. N. 1993b; Association of themcrD gene product with methyl-coenzyme M reductase inMethanococcus vannielii.. Biochim Biophys Acta 1203:175–183
     [Google Scholar]
264. Stupperich E., Juza A., Hoppert M., Mayer F. 1993; Cloning, sequencing, and immunological characterization of the corrinoid-containing subunit of the N⁵-methyltetrahydromethanopterin: coenzyme M methyltransferase fromMethanobacterium thermoautotrophicum.. Eur J Biochem 217:116–121
     [Google Scholar]
265. Suh M.P., Oh K.Y., Lee J.W., Bae Y.Y. 1996; Acetamide coordination in a nickel(I) macrocyclic complex: synthesis, properties, and X-ray crystal structure of a five-coordinate nickel(I) iminol complex of 1,3,6,8,12,15-hexaazatri- cyclo[13.3.1.1^8,12]icosane.. J Am Chem Soc 118:777–783
     [Google Scholar]
266. Tada M., Masuzawa Y. 1997; Biomimetic methane generation and disulfide formation by catalysis with a nickel complex.. Chem Commun 22:2161–2162
     [Google Scholar]
267. Tallant T.C., Krzycki J.A. 1996; Coenzyme M methylase activity of the 480-kilodalton corrinoid protein fromMethanosarcina barkeri.. J Bacteriol 175:1295–1301
     [Google Scholar]
268. Tallant T.C., Krzycki J.A. 1997; Methylthiol: coenzyme M methyltransferase fromMethanosarcina barkeri, an enzyme of methanogenesis from dimethylsulfide and methylmercapto- propionate.. J Bacteriol 179:6902–6911
     [Google Scholar]
269. Tanaka K. 1994; Anaerobic degradation of tetramethyl-ammonium by a newly isolated marine methanogen.. J Ferment Bioeng 78:386–388
     [Google Scholar]
270. Taylor C. D., Wolfe R. S. 1974a; Structure and methylation of coenzyme M (H&H₂CH₂SO₃).. J Biol Chem 249:4879–4885
     [Google Scholar]
271. Taylor C. D., Wolfe R. S. 1974b; A simplified assay for coenzyme M (H&H₂CH₂SO₃).. J Biol Chem 249:4886–4890
     [Google Scholar]
272. Te Brömmelstroet B.W., Hensgens C.M.H., Geerts W.J., Keltjens J.T., van der Drift C., Vogels G.D. 1990; Purification and properties of 5,10-methenyltetrahydromethanopterin cyclohydrolase fromMethanosarcina barkeri.. J Bacteriol 172:564–571
     [Google Scholar]
273. Te Brömmelstroet B.W., Geerts W.J., Keltjens J.T., van der Drift C., Vogels G.D. 1991; Purification and properties of 5.10-methylenetetrahydromethanopterin dehydrogenase and 5.10-methylenetetrahydromethanopterin reductase, two coenzyme F₄₂₀-dependent enzymes, fromMethanosarcina barkeri.. Biochim Biophys Acta 1079:293–302
     [Google Scholar]
274. Telser J. 1998; Nickel in F₄₃₀.. In Bioinorganic Chemistry: Trace Element Evolution from Anaerobes to Aerobes 91 pp. 31–63 Edited by Williams R. J. P. Heidelberg: Springer;
     [Google Scholar]
275. Telser J., Fann Y.-C., Renner M.W., Fajer J., Wang S.K., Zhang H., &ott R.A., Hoffman B. M. 1997; Investigation by EPR and ENDOR spectro&opy of the Ni(I) form of cofactor F₄₃₀ ofMethanobacterium thermoautotrophicum and of Ni(I) octa-ethylisobacteriochlorin.. J Am Chem Soc 119:733–743
     [Google Scholar]
276. Tersteegen A., Linder D., Thauer R.K., Hedderich R. 1997; Structures and functions of four anabolic 2-oxoacid oxido- reductases inMetbanobacterium tbermoautotrophicum.. Eur J Biocbem 244:862–868
     [Google Scholar]
277. Thauer R.K. 1990; Energy metabolism of methanogenic bacteria.. Biochim Biophys Acta 1018:256–259
     [Google Scholar]
278. Thauer R.K. 1997; Biodiversity and unity in biochemistry.. Antonie Leeuwenhoek 71:21–32
     [Google Scholar]
279. Thauer R.K., Bonacker L.G. 1994; Biosynthesis of coenzyme F₄₃₀, a nickel porphinoid involved in methanogenesis.. In The Biosynthesis of the T etrapyrrole Pigments pp. 210–227 Edited by Chadwick D. J., Ackrill K. Ciba Foundation Symposium 180 Chichester: Wiley;
     [Google Scholar]
280. Thauer R.K., Kunow J. 1995; Sulfate reducing Archaea.. In Sulfate Reducing Bacteria pp. 33–48 Edited by Barton L. L. New York: Plenum;
     [Google Scholar]
281. Thauer R.K., Jungermann K., Decker K. 1977; Energy conservation in chemotrophic anaerobic bacteria.. Bacteriol Rev 41:100–180
     [Google Scholar]
282. Thauer R.K., Hedderich R., Fi&her R. 1993; Biochemistry. Reactions and enzymes involved in methanogenesis from CO₂ and H₂.. In Methanogenesis pp. 209–252 Edited by Ferry J.G. New York & London: Chapman & Hall;
     [Google Scholar]
283. Thauer R.K., Klein A.R., Hartmann G.C. 1996; Reactions with molecular hydrogen in microorganisms: evidence for a purely organic hydrogenation catalyst.. Chem Rev 96:3031–3042
     [Google Scholar]
284. Thompson H., Tersteegen A., Thauer R.K., Hedderich R. 1998; Two malate dehydrogenases inMetbanobacterium thermoautotrophicum.. Arch Microbiol 170:38–42
     [Google Scholar]
285. Vaupel M. 1993 Untersuchungen mit Metbanobacterium ther- moformicicum und Metbanobacterium formicicum zur Rolle von H₂-bildender N⁵,N¹⁰-Methylentetrahydromethanopterin-Dehy- drogenase in methanogenen Archaea Diploma thesis, Philipps-Universitat Marburg
     [Google Scholar]
286. Vaupel M., Thauer R.K. 1995; Coenzyme F₄₂₀-dependent N⁵,N¹⁰-methylenetetrahydromethanopterin reductase (Mer) fromMetbanobacterium tbermoautotrophicum strain Marburg. Cloning, sequencing, tran&riptional analysis and functional expression inE&herichia coli of themer gene.. Eur J Biochem 231:773–778
     [Google Scholar]
287. Vaupel M., Thauer R.K. 1998; Two F₄₂₀-reducing hydrogenases inMethanosarcina barkeri.. Arch Microbiol 169:201–205
     [Google Scholar]
288. Vaupel M., Dietz H., Linder D., Thauer R.K. 1996; Primary structure of cyclohydrolase (Mch) fromMetbanobacterium tbermoautotrophicum (strain Marburg) and functional expresäsion of themch gene inE&herichia coli.. Eur J Biochem 236:294–300
     [Google Scholar]
289. Vaupel M., Vorholt J.A., Thauer R.K. 1998; Overproduction and one-step purification of the N⁵,N¹⁰-methenyltetrahydro-methanopterin cyclohydrolase (Mch) from the hyperthermophilicMethanopyrus kandleri.. Extremophiles 2:15–22
     [Google Scholar]
290. Vermeij P., Detmers F.J.M., Broers F.J.M., Keltjens J.T., van der Drift C. 1994; Purification and characterization of coenzyme F₃₉₀ synthetase fromMetbanobacterium tbermoautotrophicum(strain ΔH).. Eur J Biochem 226:185–191
     [Google Scholar]
291. Vermeij P., Vinke E., Keltjens J.T., van der Drift C. 1995; Purification and properties of coenzyme F₃₉₀ hydrolase fromMetbanobacterium tbermoautotrophicum (strain Marburg).. Eur J Biochem 234:592–597
     [Google Scholar]
292. Vermeij P., van der Steen R.J.T., Keltjens J.T., Vogels G.D., Leisinger T. 1996; Coenzyme F₃₉₀ synthetase fromMethano-bacterium tbermoautotrophicum Marburg belongs to the super-family of adenylate-forming enzymes.. J Bacteriol 178:505–510
     [Google Scholar]
293. Vogel G. 1998; Did the first complex cell eat hydrogen ?. &ience 279:1633–1634
     [Google Scholar]
294. Vorholt J.A., Thauer R.K. 1997; The active species of “CO₂” utilized by formylmethanofuran dehydrogenase from methanogenic Archaea.. Eur J Biochem 248:919–924
     [Google Scholar]
295. Vorholt J., Kunow J., Stetter K.O., Thauer R.K. 1995; Enzymes and coenzymes of the carbon monoxide dehydrogenase pathway for autotrophic CO₂ fixation inArchaeoglobus lithotrophicus and the lack of carbon monoxide dehydrogenase in the heterotrophicA. profundus.. Arch Microbiol 163:112–118
     [Google Scholar]
296. Vorholt J.A., Vaupel M., Thauer R.K. 1996; A polyferredoxin with eight [4Fe-4S] clusters as a subunit of molybdenum formylmethanofuran dehydrogenase fromMethanosarcina barkeri.. Eur J Biochem 236:309–317
     [Google Scholar]
297. Vorholt J. A., Hafenbradl D., Stetter K. O., Thauer R. K. 1997a; Pathways of autotrophic C0₂ fixation and of dis- similatory nitrate reduction to N_aO inFerroglobus placidus.. Arch Microbiol 167:19–23
     [Google Scholar]
298. Vorholt J.A., Vaupel M., Thauer R.K. 1997b; A selenium-dependent and selenium-independent formylmethanofuran dehydrogenase and their tran&riptional regulation in the hyperthermophilicMethanopyrus kandleri.. Mol Microbiol 23:1033–1042
     [Google Scholar]
299. Wackett L.P., Honek J.F., Begley T.P., Wallace V., Orme-Johnson W.-H., Walsh C.T. 1987; Substrate analogues as mechanistic probes of methyl-S-coenzyme M reductase.. Biochemistry 26:6012–6018
     [Google Scholar]
300. Wassenaar R.W., Daas P.J.H., Geerts W.J., Keltjens J.T., van der Drift C. 1996; Involvement of methyltransferase-activating protein and methyltransferase 2 isoenzyme II in methylamine: coenzyme M methyltransferase reactions inMethanosarcina barkeri Fusaro.. J Bacteriol 178:6937–6944
     [Google Scholar]
301. Wassenaar R.W., Keltjens J.T., van der Drift C., Vogels G.D. 1998; Purification and characterization of dimethylamine:5- hydroxybenzimidazolyl-cobamide methyltransferase fromMethanosarcina barkeri Fusaro.. Eur J Biochem 253:692–697
     [Google Scholar]
302. Wasserfallen A. 1994; Formylmethanofuran synthesis by for mylmethanofuran dehydrogenase fromMetbanobacterium thermoautotrophicum Marburg.. Biocbem Biophys Res Commun 199:1256–1261
     [Google Scholar]
303. Wasserfallen A., Huber K., Leisinger T. 1995; Purification and structural characterization of a flavoprotein induced by iron limitation inMetbanobacterium tbermoautotrophicum Marburg.. J Bacteriol 111:2436–2441
     [Google Scholar]
304. Weiss D.S., Thauer R.K. 1993; Methanogenesis and the unity of biochemistry.. Cell 72:819–822
     [Google Scholar]
305. Weiss D.S., Gärtner P., Thauer R.K. 1994; The energetics and sodium-ion dependence of N⁵-methyltetrahydromethanopterin: coenzyme M methyltransferase studied with cob(I)alamin as methyl acceptor and methylcob(III)alamin as methyl donor.. Eur J Biochem 226:799–809
     [Google Scholar]
306. White R.H. 1994; Biosynthesis of (7-mercaptoheptanoyl)-threonine phosphate.. Biochemistry 33:7077–7081
     [Google Scholar]
307. White R.H. 1998; Methanopterin biosynthesis: methylation of the biosynthetic intermediates.. Biochim Biophys Acta 1380:257–267
     [Google Scholar]
308. White R.H., Zhou D. 1993; Biosynthesis of the coenzymes in methanogens.. In Methanogenesis pp. 409–444 Edited by Ferry J. G. New York & London: Chapman & Hall;
     [Google Scholar]
309. Whitman W.B., Wolfe R.S. 1980; Presence of nickel in factor F₄₃₀ fromMethanobacterium bryantii.. Biocbem Biophys Res Commun 92:1196–1201
     [Google Scholar]
310. Widdel F., Frimmer U. 1995; Purification of enzymes involved in alcohol utilization by methanogenic archaea.. In Archaea - A Laboratory Manual, Metbanogens pp. 263–268 Edited by Sowers K. R., &hreier H. J. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory;
     [Google Scholar]
311. Wilms R., Freiberg C., Wegerle E., Meier I., Mayer F., Müller V. 1996; Subunit structure and organization of the genes of the A₁A₀ ATPase from the archaeon Methanosarcina mazei Göl.. J Biol Chem 271:18843–18852
     [Google Scholar]
312. Wolfe R.S. 1991; My kind of biology.. Annu Rev Microbiol 45:1–35
     [Google Scholar]
313. Wolfe R.S. 1993; An historical overview of methanogenesis.. In Methanogenesis pp. 1–32 Edited by Ferry J.G. New York & London: Chapman & Hall;
     [Google Scholar]
314. Wolfe R.S. 1996; 1776-1996: Alessandro Volta’s combustible air.. ASM News 62:529–534
     [Google Scholar]
315. Won H., Olson K.D., Summers M.F., Wolfe R.S. 1993; F430- dependent biocatalysis in methanogenic archaebacteria.. Comments Inorg Cbem 15:1–26
     [Google Scholar]
316. Woods D.D. 1936; LXXVII. Hydrogenlyases. IV. The synthesis of formic acid by bacteria.. Biocbem J 30:515–527
     [Google Scholar]
317. Woods D.D. 1950; Obituary Notice. Marjory Stephenson (1885-1948).. Biocbem J 46:377
     [Google Scholar]
318. Yeliseev A., Gärtner P., Harms U., Linder D., Thauer R.K. 1993; Function of methylcobalamin: coenzyme M methyltransferase isoenzyme II inMethanosarcina barkeri.. Arch Microbiol 159:530–536
     [Google Scholar]
319. Zeikus J.G., Wolfe R.S. 1972; Methanobacterium tbermoautotropbicum sp. n., an anaerobic autotrophic, extreme thermophile.. J Bacteriol 109:707–713
     [Google Scholar]
320. Zeikus J.G., Fuchs G., Kenealy W., Thauer R.K. 1977; Oxidoreductases involved in cell carbon synthesis ofMethanobacterium thermoautotrophicum.. J Bacteriol 132:604–613
     [Google Scholar]
321. Zinder S.H. 1993; Physiological ecology of methanogens.. In Methanogenesis pp. 128–206 Edited by Ferry J.G. New York & London: Chapman & Hall;
     [Google Scholar]
322. Zirngibl C, Hedderich R., Thauer R.K. 1990; N⁵,N¹⁰- Methylenetetrahydromethanopterin dehydrogenase fromMethanobacterium thermoautotrophicum has hydrogenase activity.. FEBS Lett 261:112–116
     [Google Scholar]