Six putative two-component regulatory systems isolated from Lactococcus lactis subsp. cremoris MG1363

The GenBank accession numbers for the sequences of the six 2CSs and surrounding ORFs determined in this work are AF172649, AF176556, AF178425, AF172650, AF176557 and AF176809 for systems A–F, respectively.

References

1. Alex L. A., Simon M. J. 1994; Protein histidine kinases and signal transduction in prokaryotes and eukaryotes. Trends Genet 10:133–139 [CrossRef]
   [Google Scholar]
2. Altschul S. F., Madden T. L., Schafer A. A., Hang J., Hang Z., Miller W., Lipman D. J. 1997; Gapped blast and psi-blast: a new generation of protein database search programs. Nucleic Acids Res 25:3389–3402 [CrossRef]
   [Google Scholar]
3. Appleby J. L., Parkinson J. S., Bourett R. B. 1996; Signal transduction via the multistep phosphorelay: not necessarily a road less travelled. Cell 86:845–848 [CrossRef]
   [Google Scholar]
4. Baikalov I., Schroder I., Kaczor-Grzeskowiak M., Grzeskowiak K., Gunsalus R. P., Dickerson R. E. 1996; Structure of the Escherichia coli response regulator NarL. Biochemistry 35:11053–11061 [CrossRef]
   [Google Scholar]
5. Birnboim H. C., Doly J. 1979; A rapid alkaline lysis procedure for screening recombinant DNA. Nucleic Acids Res 7:1513–1523 [CrossRef]
   [Google Scholar]
6. Bult C. J., White O., Olsen G. J.38 other authors 1996; Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii. Science 273:1058–1073 [CrossRef]
   [Google Scholar]
7. Chang C., Meyerowitz E. M. 1994; Eukaryotes have ‘‘two component’’ signal transducers. Res Microbiol 145:481–486 [CrossRef]
   [Google Scholar]
8. De Vos W. M., Vos P., de Haards H., Boerrigter I. 1989; Cloning and expression of the Lactococcus lactis subsp. cremoris SK11 gene encoding an extracellular serine proteinase. Gene 85:169–176 [CrossRef]
   [Google Scholar]
9. Diep D. B., Havarstein L. S., Nissen-Meyer J., Nes I. F. 1994; The gene encoding plantaricin A, a bacteriocin from Lactobacillus plantarum C11 is located on the same transcription unit as an agr-like regulatory system. Appl Environ Microbiol 60:160–166
   [Google Scholar]
10. Diep D. B., Havarstein L. S., Nes I. F. 1996; Characterization of the locus responsible for bacteriocin production in Lactobacillus plantarum C11. J Bacteriol 178:4472–4483
    [Google Scholar]
11. Dubnau D. 1991; Genetic competence in Bacillus subtilis. Microbiol Rev 55:395–424
    [Google Scholar]
12. Egger L. A., Park H., Inouye M. 1997; Signal transduction via the histidyl aspartyl phosphorelay. Genes Cells 2:167–184 [CrossRef]
    [Google Scholar]
13. Fabret C., Feher V. A., Hoch J. A. 1999; Two-component signal transduction in Bacillus subtilis: how one organism sees its world. J Bacteriol 181:1975–1983
    [Google Scholar]
14. Gasson M. J. 1983; Plasmid complement of Streptococcus lactis NCDO712 and other lactic streptococci after protoplast-induced curing. J Bacteriol 154:1–9
    [Google Scholar]
15. Hoch J. A., Silhavy T. J.editors 1995 Two Component Signal Transduction Washington, DC: American Society for Microbiology;
    [Google Scholar]
16. Ishige K., Nagasawa S., Tokishita S., Mizuno T. 1994; A novel device of bacterial signal transducers. EMBO J 13:5195–5202
    [Google Scholar]
17. Israelsen H., Madsen S. M., Vrang A., Hansen E. B., Johansen E. 1995; Cloning and partial characterization of regulated promoters from Lactococcus lactis TN917-LacZ integrants with the new promoter probe vector, pAK80. Appl Environ Microbiol 61:2540–2547
    [Google Scholar]
18. Jensen P. R., Hammer K. 1998; Artificial promoters for metabolic optimization. Biotechnol Bioeng 58:192–195
    [Google Scholar]
19. Khunajakr N., Liu C. Q., Charoenchai P., Dunn N. W. 1999; A plasmid-encoded two-component regulatory system involved in copper-inducible transcription in Lactococcus lactis. Gene 229:229–235 [CrossRef]
    [Google Scholar]
20. Kuipers O. P., Beerthuyzen M. M., Siezen R. J., de Vos W. M. 1993; Characterization of the nisin gene cluster nisABTCIPR of Lactococcus lactis. Requirement of expression of the nisA and nisI genes for development of immunity. Eur J Biochem 216:281–291 [CrossRef]
    [Google Scholar]
21. Kuipers O. P., Beerthuyzen M. M., de Ruyter P. G. G., Luesink E. J., de Vos W. M. 1995; Autoregulation of nisin biosynthesis in Lactococcus lactis by signal transduction. J Biol Chem 270:27299–27304 [CrossRef]
    [Google Scholar]
22. Leenhouts K. J., Kok J., Venema G. 1989; Campbell-like integration of heterologous plasmid DNA into the chromosome of Lactococcus lactis subsp. lactis. Appl Environ Microbiol 55:394–400
    [Google Scholar]
23. Leenhouts K. J., Kok J., Venema G. 1990; Replacement recombination in Lactococcus lactis subsp. lactis. J Bacteriol 173:4794–4798
    [Google Scholar]
24. Leloup L., Ehrlich S. D., Zagorec M., Morel-Deville F. 1997; Single crossover integration in the Lactobacillus sake chromosome and insertional inactivation of the pts1 and lacL genes. Appl Environ Microbiol 63:2117–2123
    [Google Scholar]
25. Loomis W. F., Shaulsky G., Wang N. 1997; Histidine kinases in signal transduction pathways of Eukaryotes. J Cell Sci 110:1141–1145
    [Google Scholar]
26. Mizuno T. 1998; His-Asp phosphotransfer signal transduction. J Biochem 123:555–563 [CrossRef]
    [Google Scholar]
27. Mizuno T., Tanaka I. 1997; Structure of the DNA-binding domain of the OmpR family of response regulators. Mol Microbiol 24:665–667 [CrossRef]
    [Google Scholar]
28. Molenaar D., Hagting A., Alkema H., Driessen A. J. M., Konings W. N. 1993; Characteristics and osmoregulatory roles of uptake systems for proline and glycine betaine in Lactococcus lactis. J Bacteriol 175:5438–5444
    [Google Scholar]
29. Morel-Deville F., Ehrlich S. D., Morel P. 1997; Identification by PCR of genes encoding multiple response regulators. Microbiology 143:1513–1520 [CrossRef]
    [Google Scholar]
30. Morel-Deville F., Fauvel F., Morel P. 1998; Two-component signal-transducing systems involved in stress responses and vancomycin susceptibility in Lactobacillus sakei. Microbiology 144:2873–2883 [CrossRef]
    [Google Scholar]
31. Morfeldt E., Tegmark K., Avidson S. 1996; Transcriptional control of the agr-dependent virulence gene regulator, RNAIII, in Staphylococcus aureus. Mol Microbiol 21:1227–1237 [CrossRef]
    [Google Scholar]
32. Ochman H., Medhora M., Garza D., Hartl D. L. 1990; Amplification of flanking sequences by inverse PCR. In PCR Methods: a Guide to Methods and Applications pp. 219–227Edited by Innis M. A., Gelfand D. H., Sininsky J. J., White T. J. Boston: Academic Press;
    [Google Scholar]
33. O’Connell-Motherway M., Fitzgerald G. F., van Sinderen D. 1997; Cloning and sequence analysis of putative histidine protein kinases isolated from Lactococcus lactis MG1363. Appl Environ Microbiol 63:2454–2459
    [Google Scholar]
34. O’Keeffe T., Hill C., Ross R. P. 1999; Characterization and heterologous expression of the genes encoding enterocin A production, immunity, and regulation in Enterococcus faecium DPC1146. Appl Environ MIicrobiol 65:1506–1515
    [Google Scholar]
35. O’Sullivan E. 1996 The response of Lactococcus lactis subsp. cremoris 712 to acid stress PhD thesis National University of Ireland;
    [Google Scholar]
36. Pao G. M., Saier M. H. Jr 1995; Response regulators in bacterial signal transduction systems: selective domain shuffling during evolution. J Mol Evol 40:136–154 [CrossRef]
    [Google Scholar]
37. Pao G. M., Saier M. H. Jr 1997; Nonplastid eucaryotic response regulators have a monophyletic origin and evolved from their bacterial precursors in parallel with their cognate sensor kinases. J Mol Evol 44:605–613 [CrossRef]
    [Google Scholar]
38. Parkinson J. S. 1993; Signal transduction schemes in bacteria. Cell 73:857–871 [CrossRef]
    [Google Scholar]
39. Parkinson J. S., Kofoid E. C. 1992; Communication modules in bacterial signalling proteins. Annu Rev Genet 26:71–112 [CrossRef]
    [Google Scholar]
40. Pestova E. V., Havarstein L. S., Morrison D. A. 1996; Regulation of competence for genetic transformation in Streptococus pneumoniae by an auto-induced peptide pheromone and a two-component regulatory system. Mol Microbiol 21:853–862 [CrossRef]
    [Google Scholar]
41. Pujic P., Dervyn R., Sorokin A., Ehrlich S. D. 1998; The kdgRKAT operon of Bacillus subtilis: detection of the transcript and regulation by the kdgR and ccpA genes. Microbiology 144:3111–3118 [CrossRef]
    [Google Scholar]
42. Quadri L. E. N., Kleerebezem M. M., Kuipers O. P., De Vos W. M., Roy K. L., Vederas J. C., Stiles M. E. 1997; Characterization of a locus from Carnobacterium piscicola LV17B involved in bacteriocin production and immunity: evidence for global inducer-mediated transcriptional regulation. J Bacteriol 179:6163–6171
    [Google Scholar]
43. Sambrook J., Fritsch E. F., Maniatis T. 1989 Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory;
    [Google Scholar]
44. Stock J. B., Ninfa A. J., Stock A. M. 1989; Protein phosphorylation and regulation of adaptive responses in bacteria. Microbiol Rev 53:450–490
    [Google Scholar]
45. Stock J. B., Stock A. M., Mottonen J. M. 1990; Signal transduction in bacteria. Nature 334:395–400
    [Google Scholar]
46. Stock J. B., Surette M. G., Levit M., Park P. 1995; Two component signal transduction systems: structure function relationships and mechanisms of catalysis. In Two Component Signal Transduction pp. 25–51Edited by Hoch J. A., Silhavy T. J. Washington, DC: American Society for Microbiology;
    [Google Scholar]
47. Terzaghi B. E., Sandine W. E. 1975; Improved medium for lactic streptococci and their bacteriophages. Appl Microbiol 29:307–313
    [Google Scholar]
48. Van de Guchte M., Kok J., Venema G. 1992; Gene expression in Lactococcus lactis. FEMS Microbiol Rev 8:73–92
    [Google Scholar]
49. Van der Meer J. R., Polman J., Beerthuyzen M. M., Seizen R. J., Kuipers O. P., de Vos W. M. 1993; Characterization of the Lactococcus lactis nisin A operon genes nisP, encoding a subtilisin-like serine proteinase involved in precursor processing and nisR, encoding a regulatory protein involved in nisin biosynthesis. J Bacteriol 175:2578–2588
    [Google Scholar]
50. Van Rooijen R. J., de Vos W. M. 1990; Molecular cloning, transcriptional analysis, and nucleotide sequence of lacR, a gene encoding the repressor of the lactose phosphotransferase system of Lactococcus lactis. J Biol Chem 265:18499–18503
    [Google Scholar]
51. Volz K. 1995; Structural and functional conservation in response regulators. In Two Component Signal Transduction pp. 54–64Edited by Hoch J. A., Silhavy T. J. Washington, DC: American Society for Microbiology;
    [Google Scholar]