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Volume 157, Issue 7

The genome sequence of subsp. W23: insights into speciation within the complex and into the history of genetics Free

Abstract

The genome sequence of subsp. W23 has been determined. The sequence strongly suggests that W23 is a direct descendant of ATCC 6633. W23 shares a 3.6 Mb core genome with the intensively studied model organism subsp. 168, and gene order within this core has been strongly conserved. Additionally, the W23 genome has 157 accessory (that is, non-core) genome segments that are not found in 168, while the 168 genome has 141 segments not found in W23. The distribution of sequences similar to these accessory segments among other genomes of the species complex shows that those sequences having entered into the phylogeny of the complex more recently tend to be larger and more AT-rich than those having entered earlier. A simple model can account for these observations, in which parasitic or symbiotic DNAs are transferred into the genome and then are reduced in size and modified in base composition during speciation.

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  • Accepted:
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  • Published Online:
Funding
This study was supported by the:
  • National Sciences Foundation (Award 0234214)
© 2011 SGM
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2011-07-01
2024-04-18
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The genome sequence of Bacillus subtilis subsp. spizizenii W23: insights into speciation within the B. subtilis complex and into the history of B. subtilis genetics
Microbiology 157, 2033 (2011); https://doi.org/10.1099/mic.0.048520-0
/content/journal/micro/10.1099/mic.0.048520-0
/content/journal/micro/10.1099/mic.0.048520-0
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