1887

Abstract

A mixed culture of (GH79) and (CMI 91019B) produced two antibiotics, designated VI and VII, which were not elaborated when either fungus was grown alone. Chemical and spectroscopic analysis of VI, the major component, indicated that this compound was identical to hydroxyaspergillic acid. The minor component. VII, was produced in too low a yield for its identity to be established. However, partial characterization suggests that this antibiotic also belongs to the aspergillic acid group of mycotoxins.

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/content/journal/micro/10.1099/00221287-130-2-319
1984-02-01
2024-04-26
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References

  1. Anke H. 1977; Metabolic products of microorganisms. 163. Desferritriacetylfusigen, an antibiotic from Aspergillus deflectus. Journal of Antibiotics 30:125–128
    [Google Scholar]
  2. Brownlee K. A., Loraine P. K., Stephens J. 1948; The biological assay of penicillin by a modified plate method. Journal of General Microbiology 3:347–352
    [Google Scholar]
  3. Clutterbuck A. J. 1974 Aspergillus nidulans.In Handbook of Genetics 1 pp. 447–510 Edited by King R. C. New York & London: Plenum Press;
    [Google Scholar]
  4. Cole D. S. 1980; Products of Aspergillus nidulans. Aspergillus Newsletter 14:24–26
    [Google Scholar]
  5. Cole D. S., Edwards G.F.ST L., Holt G., Macdonald K. D. 1976; Antibiotic production by wild type and mutant strains of Aspergillus nidulans. In Fifth International Fermentation Symposium p. 193 Edited by Dellweg H. Berlin: Verlag Versuchs- und Lehranstalt für Spiritusfabrikation und Fermentationstechnologie;
    [Google Scholar]
  6. Ferenczy L. 1979; Fusion of protoplasts of autotrophic fungal mutants: diversity in the genetic background of nutritional complementation. In Advances in Protoplast Research pp. 55–62 Edited by Ferenczy L., Farkas G. L. Oxford: Pergamon Press;
    [Google Scholar]
  7. Holt G., Macdonald K. D. 1968; Penicillin production and its mode of inheritance in Aspergillus nidulans. Antonie van Leeuwenhoek 34:409–416
    [Google Scholar]
  8. Holt G., Saunders G. 1983; Genetics and breeding of antibiotic-producing microorganisms. Rivista di biologia 76:183–193
    [Google Scholar]
  9. Holt G., Saunders G. 1984; Genetic modification of industrial microorganisms. In Comprehensive Biotechnology 1 Edited by Moo-Young M. Oxford: Pergamon Press; (in the Press)
    [Google Scholar]
  10. Holt G., Edwards G.R.ST L., Macdonald K. D. 1976; The genetics of mutants impaired in the biosynthesis of penicillin. In Proceedings of the Second International Symposium on the Genetics of Industrial Microorganisms pp. 199–211 Edited by Macdonald K. D. London: Academic Press;
    [Google Scholar]
  11. Hopwood D. A., Chater K. F. 1980; Fresh approaches to antibiotic production. Philosophical Transactions of the Royal Society B290:313–328
    [Google Scholar]
  12. Mabayashi Y., Sumita M., Fukushine K., Yamazaki M. 1978; Isolation and structure of a red pigment from Aspergillus ochraceus. Chemical and Pharmaceutical Bulletin 26:1320–1322
    [Google Scholar]
  13. Makins J. F., Holt , Macdonald K. D. 1980; Cosynthesis of penicillin following treatment of mutants of Aspergillus nidulans impaired in antibiotic production with lytic enzymes. Journal of General Microbiology 119:397–404
    [Google Scholar]
  14. Middleton A. J., Cole D. S., Macdonald K. D. 1979; A hydroxamic acid from Aspergillus nidulanswith antibiotic activity against Proteus species. Journal of Antibiotics 31:1110–1115
    [Google Scholar]
  15. Perry M. J., Adlard M. W., Holt G. 1982a; The isolation of a fungal metabolite which exhibits synergy with sterigmatocystin. Journal of Applied Bacteriology 52:83–89
    [Google Scholar]
  16. Perry M. J., Adlard M. W., Holt G. 1982b; The effect of the synergy between sterigmatocystin and a fungal metabolite on Bacillus subtilis. Journal of Applied Bacteriology 52:91–96
    [Google Scholar]
  17. Pontecorvo G., Roper J. A., Hemmons L. M., Macdonald K. D., Bufton A.W.J. 1953; The genetics of Aspergillus nidulans. Advances in Genetics 5:141–238
    [Google Scholar]
  18. Steyn P. S. 1980 The Biosynthesis of Mycotoxins London: Academic Press;
    [Google Scholar]
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