RT Journal Article SR Electronic(1) A1 Woodward, S. A1 Sultan, H. Y. A1 Barrett, D. K. A1 Pearce, R. B.YR 1993 T1 Two new antifungal metabolites produced by Sparassis crispa in culture and in decayed trees JF Microbiology, VO 139 IS 1 SP 153 OP 159 DO https://doi.org/10.1099/00221287-139-1-153 PB Microbiology Society, SN 1465-2080, AB The basidiomycete fungus Sparassis crispa produced three antifungal compounds during submerged culture in 2% malt broth. One compound appeared to be sparassol (methyl-2-hydroxy-4-methoxy-6-methylbenzoate), first characterized in 1924. The other two, termed ScI and ScII, exhibited considerably greater antifungal activity than did sparassol against Cladosporium cucumerinum, and were characterized as methyl-2,4-dihydroxy-6-methylbenzoate (methyl orsellinate) and an incompletely determined methyl-dihydroxy-methoxy-methylbenzoate, respectively. Both compounds were found in the decayed wood of trees, where their presence was diagnostic of S. crispa infection. The possible ecological role of these compounds is discussed., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-139-1-153