1887

Abstract

SUMMARY: The flagellate requires vitamin B and responds only to those natural forms of the vitamin which are active also for higher animals. The relation between the rate of growth and the concentration of cyano- cobalamin is described by an equation of the form of an adsorption isotherm. The ‘inactive’ analogues, pseudovitamin B and Factor A, were taken up by to about the same degree as cyanocobalamin, and inhibited competitively the growth response to cyanocobalamin, apparently by blocking a cell mechanism for ‘ binding ’ the vitamin.

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/content/journal/micro/10.1099/00221287-19-1-161
1958-08-01
2024-04-28
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References

  1. Coates M. E., Davies M. K., Dawson R., Harrison G. F., Holdsworth E. S., Kon S. K., Porter J. W. G. 1956; The activity for chicks of some vitamin B12-like compounds. Biochem. J 64:682
    [Google Scholar]
  2. Coates M. E., Ford J. E. 1955; Methods of measurement of vitamin B12. Biochem. Soc. Symp 13:36
    [Google Scholar]
  3. Coates M. E., Ford J. E., Harrison G. F., Kon S. K., Porter J. W. G. 1953; Vitamin B12-like compounds. Brit. J. Nutr 7:319
    [Google Scholar]
  4. Daisley K. W. 1957; Vitamin B12 in marine ecology. Nature; Land: 1801043
    [Google Scholar]
  5. Droop M. R. 1957a; Auxotrophy and organic compounds in the nutrition of marine phytoplankton. J. gen. Microbiol 16:286
    [Google Scholar]
  6. Droop M. R. 1957b; Vitamin B12 in marine ecology. Nature; Lond: 1801041
    [Google Scholar]
  7. Ford J. E. 1953; The specificity of the requirement of Ochromonas malhamensis for cyanocobalamin. Brit. J. Nutr 7:299
    [Google Scholar]
  8. Ford J. E., Hutner S. H. 1955; Vitamin B12 in the metabolism of micro-organisms. Vitam. & Horm 13:101
    [Google Scholar]
  9. Ford J. E., Hutner S. H. 1957; On the nature of the vitamin B12 requirement in soil bacteria isolated by Lochhead and his co-workers. Canad. J. Microbiol 3:319
    [Google Scholar]
  10. Ford J. E., Kon S. K., Porter J. W. G. 1952; Cobalt in ruminant nutrition. Chem. & Ind p. 495:
    [Google Scholar]
  11. Gregory M. E. 1954; The microbiological assay of vitamin B12 in the milk of different animal species. Brit. J. Nutr 8:340
    [Google Scholar]
  12. Gregory M. E., Holdsworth E. S. 1953; The combination of some vitamin B12-like compounds with sow’s milk whey and ‘intrinsic factor’ concentrates. Biochem. J 55:830
    [Google Scholar]
  13. Hendlin D. 1953; Discussion of papers on vitamin B12. Ann. N.Y. Acad. Sci 56:870
    [Google Scholar]
  14. Hinshelwood C. N. 1946 The chemical kinetics of the bacterial cell Oxford: University Press;
    [Google Scholar]
  15. Hutner S. H., Provasoli L., Filfus J. 1953; Nutrition of some phagotrophic freshwater chrysomonads. Ann. N. Y. Acad. Sci 56:852
    [Google Scholar]
  16. Hutner S. H., Sanders M., Mclaughlin J. J. A., Scher S. 1957; Electrolyte requirements of protists and archaeometabolism. Ann. N.Y. Acad. Sci 69:286
    [Google Scholar]
  17. Kon S. K. 1955; Other factors related to vitamin B12. Biochem. Soc. Symp 13:17
    [Google Scholar]
  18. Kristensen H. P. O. 1955; Investigations into the Euglena gracilis method for quantitative assay of vitamin B12. Acta physiol, scand 33:232
    [Google Scholar]
  19. Lochhead A. G., Burton M. O. 1955; Characteristics of vitamin B12-requiring bacteria. Canad. J. Microbiol 1:319
    [Google Scholar]
  20. Lochhead A. G., Thexton R. H. 1951; Vitamin Bla as a growth factor for soil bacteria. Nature; Lond: 1671034
    [Google Scholar]
  21. Oginsky E. L., Smith P. H. 1953; Effect of vitamin B12 derivatives on oxidation and vitamin uptake by Escherichia coli. J. Bact 65:183
    [Google Scholar]
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