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Abstract
SUMMARY: The growth-promoting action of β-alanine on Saccharomyces carls-bergensis and two strains of S. cerevisiae is stimulated or inhibited to different extents by the optical enantiomorphs of methionine, glutamic acid, asparagine and a-alanine. This behaviour can be considered as due, in each individual case, to one or more of three separate effects: (a) stimulatory, (b) inhibitory, and (c) antagonistic. In general, the l-forms of the amino-acids have a more pronounced action than the d-isomers. Racemic mixtures have intermediate effects. Similar but less striking results are observed when β-alanine is replaced by pantothenic acid. Atypical effects are obtained with d-alanine and d-glutamic acid.
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© Society for General Microbiology 1951