%0 Journal Article %A Iordanescu, S. %A Surdeanu, Marietta %T Two Restriction and Modification Systems in Staphylococcus aureusnctc8325 %D 1976 %J Microbiology, %V 96 %N 2 %P 277-281 %@ 1465-2080 %R https://doi.org/10.1099/00221287-96-2-277 %I Microbiology Society, %X SUMMARY: The presence of two distinct host specificities in Staphylococcus aureus strain nctc8325 was revealed by the isolation of restriction- and modification-deficient mutants. The two host specificity systems, designated S1 and S2, are both active on phage 80μ α but are not additive in their restricting activity. Restriction-deficient, modification-proficient mutants were invariably affected in both restriction systems. The functional relationship between these two systems is discussed. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-96-2-277