1887

Abstract

is one of the major model systems in biology based on advantageous properties such as short life span, transparency, genetic tractability and ease of culture using an diet. In its natural habitat, compost and rotting plant material, this nematode lives on bacteria. However, is a predator of bacteria, but can also be infected by nematopathogenic coryneform bacteria such and species, which display intriguing and diverse modes of pathogenicity. Depending on the nematode pathogen, aggregates of worms, termed worm-stars, can be formed, or severe rectal swelling, so-called Dar formation, can be induced. Using the human and animal pathogens and as well as the non-pathogenic species , we show that these coryneform bacteria can also induce star formation slowly in worms, as well as a severe tail-swelling phenotype. While had a significant, but minor influence on survival of , nematodes were killed after infection with and . The two pathogenic species were avoided by the nematodes and induced aversive learning in .

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2016-01-01
2024-03-28
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