RT Journal Article SR Electronic(1) A1 Carro, Lorena A1 Pujic, Petar A1 Alloisio, Nicole A1 Fournier, Pascale A1 Boubakri, Hasna A1 Poly, Franck A1 Rey, Marjolaine A1 Heddi, Abdelaziz A1 Normand, PhilippeYR 2016 T1 Physiological effects of major up-regulated Alnus glutinosa peptides on Frankia sp. ACN14a JF Microbiology, VO 162 IS 7 SP 1173 OP 1184 DO https://doi.org/10.1099/mic.0.000291 PB Microbiology Society, SN 1465-2080, AB Alnus glutinosa has been shown previously to synthesize, in response to nodulation by Frankia sp. ACN14a, an array of peptides called Alnus symbiotic up-regulated peptides (ASUPs). In a previous study one peptide (Ag5) was shown to bind to Frankia nitrogen-fixing vesicles and to modify their porosity. Here we analyse four other ASUPs, alongside Ag5, to determine whether they have different physiological effects on in vitro grown Frankia sp. ACN14a. The five studied peptides were shown to have different effects on nitrogen fixation, respiration, growth, the release of ions and amino acids, as well as on cell clumping and cell lysis. The mRNA abundance for all five peptides was quantified in symbiotic nodules and one (Ag11) was found to be more abundant in the meristem part of the nodule. These findings point to some peptides having complementary effects on Frankia cells., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.000291