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Volume 163, Issue 8

Microbe Profile: : a shape-changing, opportunistic pathogenic fungus of humans Open Access

This article is part of the Microbe Profiles collection.

Abstract

is normally a harmless commensal of human beings, but it can cause superficial infections of the mucosa (oral/vaginal thrush) in healthy individuals and (rarely) infections of the skin or nails. It can also become invasive, causing life-threatening systemic and bloodstream infections in immunocompromised hosts, where the mortality rate can be as high as 50 %. It is the most common cause of serious fungal infection and is a common cause of nosocomial infections in hospitals. Some strains have been recognized that are resistant to azoles or echinocandins, which are the first-line antifungals for treatment of infections.

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Keyword(s): Candida albicans , drug resistance , immune response , Medical Mycology , morphogenesis and pathogenesis
© 2017 The Authors
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/content/journal/micro/10.1099/mic.0.000499
2017-08-01
2024-04-23
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