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Volume 158, Issue 8

An oscillating Min system in influences asymmetrical septation during sporulation Free

Abstract

The Min system plays an important role in ensuring that cell division occurs at mid-cell in rod-shaped bacteria. In pole-to-pole oscillation of the Min proteins specifically inhibits polar septation. This system also prevents polar division in during vegetative growth; however, the Min proteins do not oscillate in this organism. The Min system of plays a distinct role during sporulation, a process of differentiation which begins with an asymmetrical cell division. Here, we show that oscillation of the Min proteins can be reproduced following their introduction into cells. Further, we present evidence that the oscillatory behaviour of the Min system inhibits sporulation. We propose that an alternative Min system mechanism avoiding oscillation is evolutionarily important because oscillation of the Min system is incompatible with efficient asymmetrical septum formation and sporulation.

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2012-08-01
2024-04-18
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An oscillating Min system in Bacillus subtilis influences asymmetrical septation during sporulation
Microbiology 158, 1972 (2012); https://doi.org/10.1099/mic.0.059295-0
/content/journal/micro/10.1099/mic.0.059295-0
/content/journal/micro/10.1099/mic.0.059295-0
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