1887

Abstract

The levels of resistance to nystatin induced in 16 strains of by a few subcultures in the presence of the drug were high (minimum inhibitory concentrations > 20000 U ml) compared with those obtained in 12 strains of ( inhibitory concentrations ≤ 2000 U ml). The results suggest a high rate of mutation in the first species.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-118-1-263
1980-05-01
2024-05-17
Loading full text...

Full text loading...

/deliver/fulltext/micro/118/1/mic-118-1-263.html?itemId=/content/journal/micro/10.1099/00221287-118-1-263&mimeType=html&fmt=ahah

References

  1. Athar M. A., Winner H. I. 1971; The development of resistance by Candida species to polyene antibiotics in vitro. . Journal of Medical Microbiology 4:505–517
    [Google Scholar]
  2. Bodenhoff J. 1968; Development of strains of Cryptococcus neoformans resistant to nystatin, amphotericin B, trichomycin and polymyxin B.. Acta pathologica et microbiologica scandinavica 73:572–582
    [Google Scholar]
  3. Hamilton-Miller J. M. T. 1972a; Sterols from polyene-resistant mutants of Candida albicans. . Journal of General Microbiology 73:201–203
    [Google Scholar]
  4. Hamilton-Miller J. M. T. 1972b; Physiological properties of mutagen-induced variants of Candida albicans resistant to polyene antibiotics.. Journal of Medical Microbiology 5:425–440
    [Google Scholar]
  5. Hamilton-Miller J. M. T. 1973; Chemistry and biology of the polyene macrolide antibiotics.. Bacteriological Reviews 37:166–196
    [Google Scholar]
  6. Johnson B., White B. J., Williamson G. M. 1978; Factors influencing the susceptibility of Candida albicans to the polyenic antibiotics nystatin and amphotericin B.. Journal of General Microbiology 104:325–333
    [Google Scholar]
  7. Lodder J., Kreger-Van Rij N. J. W. 1967 The Yeasts. A Taxonomic Study., 2nd. Amsterdam:: North Holland.;
    [Google Scholar]
  8. Lövgren T., Salmela I. 1978; In vitro sensitivity of Trichomonas vaginalis and Candida albicans to chemotherapeutic agents.. Acta pathologica et microbiologica scandinavica B86:155–158
    [Google Scholar]
  9. Molzahn S. W., Woods R. A. 1972; Polyene resistance and the isolation of sterol mutants in Saccharomyces cerevisiae. . Journal of General Microbiology 72:339–348
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-118-1-263
Loading
/content/journal/micro/10.1099/00221287-118-1-263
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error