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Abstract
Summary: Bacteriophages were isolated from several strains of Pseudomonas pyocyanea and were assayed against an indicator strain. Counts of up to 1010/ml. were obtained in both broth and a denned medium. The phages are stable at 60° but rapidly inactivated at 65°. They are unaffected by 50 % glycerol and are stable at pH 6·5–10·0 but not below 6·5.
About 500 compounds have been tested for their inhibitory action on the development of these bacteriophages. All the sulphonamides, amidines, pyrimidines, organo-metallic compounds, plant extracts, mould cultures and antibiotics tested were inactive at concentrations permitting the growth of the host. Proflavine exerted a viristatic effect while notatin and hydrogen peroxide were lethal in a defined medium but not in broth.
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