1887

Abstract

SUMMARY:

Seven strains antagonistic to indicator corynebacteria on solid media were found among 100 strains of human origin. These inhibitory strains all gave sharply defined inhibition zones, belonged to bacteriophage type 71, and were isolated from superficial infections. They were strongly active in direct antagonism tests against all the other ‘aureus’ strains, and against some coagulase-negative staphylococci, streptococci and other Gram-positive species; Gram-negative organisms were not susceptible. strains producing hazy inhibition zones with corynebacteria showed similar though less extensive antibacterial activity. Inhibition by both kinds of staphylococci occurred under several different environmental conditions, but not in the presence of oleic acid. The antagonistic agents were relatively heat resistant, passed readily through cellophan, and showed considerable specificity in their action.

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/content/journal/micro/10.1099/00221287-31-3-471
1963-06-01
2024-05-05
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References

  1. Abbott J. D., Shannon R. 1958; A method for typing Shigella sonnet using colicine production as a marker. J. clin. Path. 11:71
    [Google Scholar]
  2. Alder V. G., Gillespie W. A., Herdan G. 1953; Production of opacity in egg-yolk broth by staphylococci from various sources. J. Path. Bact. 66:205
    [Google Scholar]
  3. Anderson E. S., Williams R. E. O. 1956; Bacteriophage typing of enteric pathogens and staphylococci, and its use in epidemiology. A review. J. clin. Path. 9:94
    [Google Scholar]
  4. Barrow G. I. 1955; Clinical and bacteriological aspects of impetigo contagiosa. J. Hyg., Camb. 53:495
    [Google Scholar]
  5. Barrow G. I. 1961; An outbreak of streptococcal infection caused by different strains. Mon. Bull. Minist. Hlth Lab. Sew. 20:224
    [Google Scholar]
  6. Barrow G. I., Ellis C. 1962; Colicine typing of Shigella sonnet by replicate multiple-slide inoculation of indicator organisms. Mon. Bull. Minist. Hlth Lab. Sew. 21:141
    [Google Scholar]
  7. Cooper K. E., Linton A. H., Sehgal S. N. 1958; The effect of inoculum size on inhibition zones in agar media using staphylococci and streptomycin. J. gen. Microbiol. 18:670
    [Google Scholar]
  8. Florey H. W., Chain E., Heatley N. G., Jennings M. A., Sanders A. G., Abraham E. P., Florey M. Ε. 1949 Antibiotics 1493 London: Oxford University Press;
  9. Frédéricq P. 1946; Sur la sensibilité et l’activité antibiotique des staphylocoques. CR. Soc. Biol., Paris 140:1167
    [Google Scholar]
  10. Frédéricq P. 1957; Colicins. Annu. Rev. Microbiol. 11:7
    [Google Scholar]
  11. Gardner J. F. 1949; An antibiotic produced by Staphylococcus aureus. Brit. J. exp. Path. 30:130
    [Google Scholar]
  12. Gooder H. 1961; Association of a serum opacity reaction with serological type in Streptococcus pyogenes. J. gen. Microbiol. 25:347
    [Google Scholar]
  13. Gratia A. 1946; Techniques sélectives pour la recherche systématique des germes antibiotiques. CR. Soc. Biol. Paris 140:1053
    [Google Scholar]
  14. Halbert S. P., Swick L., Sonn C. 1953; Characteristics of antibiotic-producing strains of the ocular bacterial flora. J. Immunol. 70:400
    [Google Scholar]
  15. Murray R. G. E., Loeb L. J. 1950; Antibiotics produced by micrococci and streptococci that show selective inhibition within the genus Streptococcus. Canad. J. Res. (E) 28:177
    [Google Scholar]
  16. Parker M. T. 1958; Some cultural characteristics of Staphylococcus aureus strains from superficial skin infections. J. Hyg., Camb. 56:238
    [Google Scholar]
  17. Parker M. T., Simmons L. E. 1959; The inhibition of Corynebacterium diphtheriae and of other Gram-positive organisms by Staphylococcus aureus. J. gen. Microbiol. 21:457
    [Google Scholar]
  18. Parker M. T., Tomlinson A. J. H., Williams R. E. O. 1955; Impetigo contagiosa. The association of certain types of Staphylococcus aureus and of Streptococcus pyogenes with superficial skin infections. J. Hyg., Camb. 53:458
    [Google Scholar]
  19. Rosebury T., Gale D., Taylor D. F. 1954; An approach to the study of interactive phenomena among micro-organisms indigenous to man. J. Bact. 67:135
    [Google Scholar]
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