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Abstract
Summary: A Pseudomonas isolate which utilizes azelaic acid as the sole carbon source was isolated from garden soil. Two different variants of the microorganisms were obtained from the original culture in azelaic acid medium. One variant (s), exhibited uniform turbidity which clarified rapidly after maximal growth was obtained. The second variant (T) grew in aggregates and clumps. Both variants gave normal growth curves with a maximal stationary phase in medium with glucose or in azelate medium with high osmotic pressure. The double role of azelaic acid as a source of carbon and as a harmful agent is discussed. It was concluded that when the concentration of azelate is low enough and its action not prolonged it caused cytological disturbances which were not easy to observe (variant s). But the prolonged action of azelaic acid resulted in phenotypical changes that were partially inheritable even in its absence (variant T).
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