1887

Abstract

SUMMARY: The toxicities of strains of trachoma and inclusion conjunctivitis viruses differing in virulence for the chick embryo were compared at different times during their growth in the chick embryo yolk sac. As measured by the ability to kill mice and to induce skin lesions in guinea-pigs, toxicity increased until the time at which embryos began to die. All strains possessed similar particle: toxin ratios. It is considered unlikely that the differing virulence of the strains depends on differences in the amount of toxin per elementary body.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-37-2-271
1964-11-01
2024-05-03
Loading full text...

Full text loading...

/deliver/fulltext/micro/37/2/mic-37-2-271.html?itemId=/content/journal/micro/10.1099/00221287-37-2-271&mimeType=html&fmt=ahah

References

  1. Collier L. H., Sowa J. 1958; Isolation of trachoma virus in embryonate eggs. Lancet i:993
    [Google Scholar]
  2. Dulbecco R., Vogt M. 1954; Plaque formation and isolation of pure lines with poliomyelitis virus. J. exp. Med 99:2
    [Google Scholar]
  3. Gear J. H. S., Gordon F. B., Jones B. R., Bell S. D. Jr. 1963; Nomenclature of isolates of virus from trachoma and inclusion blennorrhoea. Nature, Lond 197:26
    [Google Scholar]
  4. Jones B. R. 1961; TRIC virus infections in London. Trans. Ophthal. Soc. U.K 81:367
    [Google Scholar]
  5. Manire G. P., Smith K.O. 1959; Quantitative studies on meningopneumonitis virus. J Bact 78:523
    [Google Scholar]
  6. Murray E. S., Bell S. D. Jr., Hanna A. T., Nichols R. L., Snyder J. C. 1960; Studies on trachoma. 1. Isolation and identification of strains of elementary bodies from Saudi Arabia and Egypt. Amer. J. Trop. Med. Hyg 9:116
    [Google Scholar]
  7. Reed L. J., Muench H. 1938; A simple method of estimating fifty per cent endpoints. Amer. J. Hyg 27:493
    [Google Scholar]
  8. Reeve P. 1964; Trachoma viruses isolated in the United States. VII. Related toxicity of different strains for white mice Proc. Soc. exp. Biol., N.Y 116:373
    [Google Scholar]
  9. Reeve P., Taverne J. 1962; A simple method for total particle counts of trachoma and inclusion blennorrhoea virus. Nature, Lond 195:923
    [Google Scholar]
  10. Reeve P., Taverne J. 1963; Observations on the growth of trachoma and inclusion blennorrhoea viruses in embryonate eggs. J. Hyg., Camb 61:67
    [Google Scholar]
  11. T’ang F. F., Chang H. L., Huang Y. T., Wang K. C. 1957; Studies on the etiology of trachoma with special reference to isolation of the virus in chick embryo. Chin. med. J 75:49
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-37-2-271
Loading
/content/journal/micro/10.1099/00221287-37-2-271
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error