1887

Abstract

SUMMARY: The genetic properties of a new () host specificity of were investigated using bacteriophage L. Phage L is a better substrate for s-specific restriction than phage P22. Mutants deficient in s-restriction only were found at the same frequency as mutants deficient in both restriction and modification. Crosses between Hfr and F or between and showed that the s system has the same chromosomal location as the k system of The s system was introduced into and found to be effective on phage λ.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-69-3-345
1971-12-01
2024-05-05
Loading full text...

Full text loading...

/deliver/fulltext/micro/69/3/mic-69-3-345.html?itemId=/content/journal/micro/10.1099/00221287-69-3-345&mimeType=html&fmt=ahah

References

  1. Arber W., Dussoix D. 1962; Host specificity of DNA produced by Escherichia coli. I. Host controlled modification of bacteriophage λ. Journal of Molecular Biology 5:18–36
    [Google Scholar]
  2. Arber W., Linn S. 1969; DNA modification and restriction. Annual Review of Biochemistry 38:467–500
    [Google Scholar]
  3. Arber W., Wauters-Willems D. 1970; Host specificity of DNA produced by Escherichia coli. XII. The two restriction and modification systems of strain 15T. Molecular and General Genetics 108:203–217
    [Google Scholar]
  4. Bezdek M., Amati P. 1967; Properties of P22 and a related Salmonella typhimurium phage. I. General features and host specificity. Virology 31:272–278
    [Google Scholar]
  5. Boyer H. W. 1964; Genetic control of restriction and modification in Escherichia coli. Journal of Bacteriology 88:1652–1660
    [Google Scholar]
  6. Boyer H. W., Roulland-Dussoix D. 1969; A complementation analysis of the restriction and modification of DNA in Escherichia coli. Journal of Molecular Biology 41:459–472
    [Google Scholar]
  7. Colson C., Colson A. M. 1967; Host specificity and fertility in Salmonella typhimurium lt7. Biochemical and Biophysical Research Communications 29:692–695
    [Google Scholar]
  8. Colson A. M., Colson C., Van Pel A. 1969; Host-controlled restriction mutants of Salmonella typhimurium. Journal of General Microbiology 58:57–64
    [Google Scholar]
  9. Colson C., Colson A. M., Van Pel A. 1970; Chromosomal location of host specificity in Salmonella typhimurium. Journal of General Microbiology 60:265–271
    [Google Scholar]
  10. Colson C., Glover S. W., Symonds N., Stacey K. A. 1965; The location of the genes for host-controlled modification and restriction in Escherichia coli K12. Genetics 52:1043–1050
    [Google Scholar]
  11. Glover S. W. 1970; Functional analysis of host specificity mutants in Escherichia coli. Genetical Research 15:237–250
    [Google Scholar]
  12. Glover S. W., Colson C. 1969; Genetics of host-controlled restriction and modification in Escherichia coli. Genetical Research 13:227–240
    [Google Scholar]
  13. Hubacek J., Glover S. W. 1970; Complementation analysis of temperature sensitive host specificity mutations in Escherichia coli. Journal of Molecular Biology 50:111–127
    [Google Scholar]
  14. Taylor A. L., Trotter C. D. 1967; Revised linkage map of Escherichia coli. Bacteriological Reviews 31:332–353
    [Google Scholar]
  15. Wood W. B. 1966; Host specificity of DNA produced by Escherichia coli: bacterial mutations affecting the restriction and modification of DNA. Journal of Molecular Biology 16:118–133
    [Google Scholar]
  16. Zinder N. D. 1960; Hybrids of Escherichia and Salmonella. Science; New York: 131813–815
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-69-3-345
Loading
/content/journal/micro/10.1099/00221287-69-3-345
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error