1887

Microbiology Society logo

Volume 7, Issue 3-4

Variation in the Antigenic Composition of Staphylococcal Coagulase Free

Abstract

SUMMARY: Four different antigenic types of coagulase were identified. Antisera were prepared in rabbits against three of these, and a specific antiserum against the fourth was found in a normal human. The coagulases of all but two of the human strains examined were inhibited by one or other of two of these antisera and in a few cases by both; in addition antibodies of the same type were present in the sera of the majority of a group of normal adults. The coagulases produced by thirty-five animal strains were inhibited by the other two antisera, but further work is needed on the coagulases found in animal strains.

  • Received:
  • Published Online:
© Society for General Microbiology, 1952
Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-7-3-4-320
1952-11-01
2024-05-05
Loading full text...

Full text loading...

/deliver/fulltext/micro/7/3-4/mic-7-3-4-320.html?itemId=/content/journal/micro/10.1099/00221287-7-3-4-320&mimeType=html&fmt=ahah

References

  1. Bekker J. H. 1947; Studies on staphylocoagulase. II. Antistaphylocoagulase in human serum. Antonie van Leeuwenhoek J. Microbiol. Serol 13:128
     [Google Scholar]
  2. Duthie E. S., Lorenz L. 1952; Staphylococcal coagulase: mode of action and antigenicity. J. gen. Microbiol 6:95
     [Google Scholar]
  3. Hale J. H., Smith W. 1945; The influence of coagulase on the phagocytosis of staphylococci. Brit. J. exp. Path 26:209
     [Google Scholar]
  4. Lominski I., Roberts G. B. 1946; A substance in human serum inhibiting staphylocoagulase. J. Path. Bact 58:187
     [Google Scholar]
  5. Rammelkamp C. H., Hezebicks M. M., Dingle J. H. 1950; Specific coagulases of Staphylococcus aureus. J. exp. Med 91:295
     [Google Scholar]
  6. Smith W., Hale J. H., Smith M. M. 1947; The role of coagulase in staphylococcal infections. Brit. J. exp. Path 28:57
     [Google Scholar]
  7. Tager M., Hales H. B. 1948; Differences in the resistance of human plasmas to staphylocoagulase. Yale J. Biol. Med 21:91
     [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-7-3-4-320
Loading
Variation in the Antigenic Composition of Staphylococcal Coagulase
Microbiology 7, 320 (1952); https://doi.org/10.1099/00221287-7-3-4-320
/content/journal/micro/10.1099/00221287-7-3-4-320
/content/journal/micro/10.1099/00221287-7-3-4-320
Loading

Data & Media loading...

Most cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error