1887

Abstract

SUMMARY:

An ultradian oscillation is described for which meets the criteria for a cellular clock, i.e. timekeeping device. The rhythm can be induced by transfer from circadian conditions (stationary phase or very slow growth) to ultradian conditions (rapid growth). It can also be synchronized by ultradian temperature cycles of 6°C difference. Released to constant temperature, the rhythm persists for 20 h without damping. The period of the free-running rhythm is temperature-compensated and in no experiment did period length fall outside the narrow range between 40 and 44 min. The parameter observed is the septum index, i.e. the percentage of cells occupying the last stage of the cell cycle in wild-type cells before final division. The results suggest control of the cell division processes by the ultradian clock.

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1995-04-01
2024-05-17
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References

  1. Balzer I., Hardeland R. 1992; Multiple ultradian frequencies in dark motility of Euglena . J Interdiscip Cycle Res 23:47–55
    [Google Scholar]
  2. Balzer I., Neuhaus-Steinmetz U., Hardeland R. 1989a; Temperature-compensation in an ultradian rhythm of tyrosine aminotransferase activity in Euglena gracilis Klebs. Experientia 45:476–477
    [Google Scholar]
  3. Balzer I., Neuhaus-Steinmetz U., Quentin E., van Wüllen M., Hardeland R. 1989b; Concomitance of circadian and circa-4-hour ultradian rhythms in Euglena gracilis . J Interdiscip Cycle Res 20:15–24
    [Google Scholar]
  4. Bashford C. L, Chance B., Lloyd D., Poole R. K. 1980; Oscillations of redox state in synchronously dividing cultures of Acanthamoeba castellanii and Schizosaccharomyces pombe . Biophys J 29:1–12
    [Google Scholar]
  5. Broda H., Brugge D., Homma K., Hastings J. W. 1986; Circadian communication between unicells? Effects on period by cell-conditioning of medium. Cell Biophys 8:47–67
    [Google Scholar]
  6. Edmunds L. N. Jr 1988 Cellular and Molecular Bases of Biological Clocks . Models and Mechanisms for Circadian Timekeeping New York:: Springer.;
    [Google Scholar]
  7. Edwards C., Statham M., Lloyd D. 1975; The preparation of large-scale synchronous cultures of the trypanosomatid, Crithidia fasciculata, by cell-size selection: changes in respiration and adenylate charge through the cell cycle . J Gen Microbiol 88:141–152
    [Google Scholar]
  8. Edwards S.W., Lloyd D. 1977; Mitochondrial adenosine triphosphatase of the fission yeast, Schizosaccharomyces pombe 972h Changes in activity and oligomycin-sensitivity during the cell cycle of catabolite-repressed and de-repressed cells. Biochem J 162:39–46
    [Google Scholar]
  9. Forsburg S. L., Nurse P. 1991; Cell cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe . Annu Rev Cell Biol 7:227–256
    [Google Scholar]
  10. Jenkins H. A., Griffiths A. J., Lloyd D. 1989; Simultaneous operation of ultradian and circadian rhythms in Chlamydomonas reinhardii . J Interdiscip Cycle Res 20:257–264
    [Google Scholar]
  11. Kämmerer J., Hardeland R. 1982; On the chronobiology of Tetrahymena. I Ultradian rhythmicity in tyrosine aminotransferase activity. J Interdiscip Cycle Res 13:297–302
    [Google Scholar]
  12. Kippert F. 1987 Temperature-compensation of ultradian rhythms in ciliates. In Cbronobiology and Cbronomedicin pp 60–64 Edited by Hildebrandt G., Moog R., Raschke F. Frankfurt:: Verlag Peter Lang;
    [Google Scholar]
  13. Kippert F. 1989; Circadian control of heat tolerance in stationary phase cultures of Schizosaccharomyces pombe . Arch Microbiol 151:177–179
    [Google Scholar]
  14. Kippert F. 1992a; Ultradian and circadian clocks - two sides of one coin?. J Interdiscip Cycle Res 23:192–196
    [Google Scholar]
  15. Kippert F. 1992b The ultradian clock and the cell cycle in Schizosaccharomyces pombe MPhil thesis; >University of Wales:
    [Google Scholar]
  16. Kippert F., Engelmann W. 1989; A circadian clock controls the cell division cycle of Schizosaccharomyces pombe growing at low temperature. Eur J Cell Biol 48:(Suppl. 26)81
    [Google Scholar]
  17. Kippert F., Ninnemann H., Engelmann W. 1991; Photosynchronization of the circadian clock of Schizosaccharomyces pombe : mitochondrial cytochrome b is an essential component. Curr Genet 19:103–107
    [Google Scholar]
  18. Lloyd D. 1992 Intracellular timekeeping : epigenetic oscillations reveal the functions of an ultradian clock. In Ultradian Rbythms in Life Processes pp 5–22 Edited by Lloyd D., Rossi E. R. London :: Springer-Verlag;
    [Google Scholar]
  19. Lloyd D., Edwards S. W. 1984 Epigenetic oscillations during the cell cycles of lower eukaryotes are coupled to a clock Life’s slow dance to the music of time. In Cell Cycle Clocks pp 27–46 Edited by Edmunds L. N. New York:: Marcel Dekker.;
    [Google Scholar]
  20. Lloyd D., Edwards S. W. 1987 Temperature-compensated ultradian rhythms in lower eukaryotes: timers for cell cycle and circadian events?. InAdvances in Chronobiology, Part A, pp 131–151 Edited by Pauly J. E., Scheving L. E. New York:: Alan R. Liss.;
    [Google Scholar]
  21. Lloyd D., Kippert F. 1987; A temperature-compensated ultradian clock explains temperature-dependent quantal cell cycle times. Symp Soc Exp Biol 40:135–155
    [Google Scholar]
  22. Lloyd D., Kippert F. 1993; Intracellular coordination by the ultradian clock. Cell Biol Internat 17:1047–1052
    [Google Scholar]
  23. Lloyd D., Stupfel M. 1991; The occurrence and functions of ultradian rhythms. Biol Rev 66:275–299
    [Google Scholar]
  24. Lloyd D., Phillips C. A., Statham M. 1978; Oscillations of respiration, adenine nucleotide levels and heat evolution in synchronous cultures ofTetrahymena pyriformis ST prepared by continuous-flow selection. J Gen Microbiol 106:19–26
    [Google Scholar]
  25. Lloyd D., Edwards S. W., Williams J. L. 1981; Oscillatory accumulation of total cellular protein in synchronous cultures of Candida utilis . FEMS Microbiol Lett 12:295–298
    [Google Scholar]
  26. Lloyd D., Edwards S. W., Fry J. C. 1982a; Temperature- compensated oscillations in respiration and cellular protein content in synchronous cultures ofAcanthamoeba castellanii . Proc Natl Acad Sci USA 79:3785–3788
    [Google Scholar]
  27. Lloyd D., Poole R. K., Edwards S. W. 1982b The Cell DivisionCycle : Temporal Control of Cellular Growth and Reproduction London:: Academic Press.;
    [Google Scholar]
  28. Lysek G. 1984; Physiology and ecology of growth and sporulation in fungi. Symp Br Mycol Soc 8:323–342
    [Google Scholar]
  29. Michel U., Hardeland R. 1985; On the chronobiology of Tetrahymena. Ⅲ. Temperature compensation and temperature dependence in the ultradian oscillation of tyrosine aminotransferase. J Interdiscip Cycle Res 16:17–23
    [Google Scholar]
  30. Mitchison J. M. 1970; Physiological and cytological methods for Schizosaccharomyces pombe . Methods Cell Biol Physiol 4:131–165
    [Google Scholar]
  31. Mitchison J. M. 1989; Cell cycle growth and periodicities. In Molecular Biology of the Fission Yeast, pp 205–242 Edited by Nasim A., Young P., Johnson B. F. New York:: Academic Press.;
    [Google Scholar]
  32. Mitchison J. M., Kinghorn M. L., Hawkins C. 1963; The growth of single cells. Ⅳ. Scbixosaccbaromyces pombe at different temperatures. Exp Cell Res 30:521–527
    [Google Scholar]
  33. Nanjundiah V. 1986; How rapidly do uncoupled oscillators desynchronize?. J Theor Biol 121:375–379
    [Google Scholar]
  34. Njus D., Gooch V. D., Hastings J. W. 1981; Precision of the Gonyaulax circadian clock. Cell Biophys 3:223–231
    [Google Scholar]
  35. Novak B., Mitchison J. M. 1986; Change in the rate of CO2 production in synchronous cultures of the fission yeast Schizosaccharomyces pombe : a periodic cell cycle event that persists after the DNA-division cycle has been blocked. J Cell Sci 86:191–206
    [Google Scholar]
  36. Novak B., Mitchison J. M. 1987; Periodic cell cycle changes in the rate of CO2 production in the fission yeast Schizosaccharomyces pombe persist after a block to protein synthesis. J Cell Sci 87:323–325
    [Google Scholar]
  37. Novak B., Mitchison J. M. 1990; Changes in the rate of oxygen consumption in synchronous cultures of the fission yeast Schizosaccharomyces pombe . J Cell Sci 96:429–433
    [Google Scholar]
  38. Poole R. K. 1977; Development of respiratory activity during the cell cycle of Schizosaccharomyces pombe 972h : respiratory oscillations and heat dissipation in cultures synchronized with 2'- deoxyadenosine. J Gen Microbiol 103:19–27
    [Google Scholar]
  39. Poole R. K., Lloyd D. 1973; Oscillations of enzyme activities during the cell cycle of a glucose-repressed fission yeast Schizosaccharomyces pombe 972h . Biochem J 136:195–207
    [Google Scholar]
  40. Poole R. K., Lloyd D., Kemp R. B. 1973; Respiratory oscillations and heat evolution in synchronously dividing cultures of the fission yeast Schizosaccharomyces pombe 972h . J Gen Microbiol 77:209–220
    [Google Scholar]
  41. Wang P. Y., Schneider H. 1980; Growth of yeasts on D-xylulose. Can J Microbiol 26:1165–1168
    [Google Scholar]
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